Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients
A Sarasini, F Baldanti, M Furione… - Journal of medical …, 1995 - Wiley Online Library
Four human cytomegalovirus (HCMV) isolates from four different AIDS patients treated with
both ganciclovir and foscarnet and not responding clinically to antiviral treatment, were …
both ganciclovir and foscarnet and not responding clinically to antiviral treatment, were …
Four dually resistant human cytomegalovirus strains from AIDS patients: single mutations in UL97 and UL54 open reading frames are responsible for ganciclovir-and …
F Baldanti, A Sarasini, E Silini, M Barbi… - … Journal of Infectious …, 1995 - europepmc.org
Four human cytomegalovirus strains with double resistance to both ganciclovir and
foscarnet were recovered from acquired immunodeficiency syndrome (AIDS) patients. The …
foscarnet were recovered from acquired immunodeficiency syndrome (AIDS) patients. The …
A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate
F Baldanti, E Silini, A Sarasini, CL Talarico… - Journal of …, 1995 - Am Soc Microbiol
Multiple human cytomegalovirus (HCMV) strains frequently coexist in patients with AIDS,
and chronic ganciclovir treatment may favor the emergence of ganciclovir-resistant viral …
and chronic ganciclovir treatment may favor the emergence of ganciclovir-resistant viral …
Prevalence of resistance in patients receiving ganciclovir for serious cytomegalovirus infection
WL Drew, RC Miner, DF Busch… - Journal of Infectious …, 1991 - academic.oup.com
Seventy-two AIDS patients treated with ganciclovir for cytomegalovirus (CMV) disease were
prospectively monitored for the development of drug-resistant virus. No resistant strains …
prospectively monitored for the development of drug-resistant virus. No resistant strains …
Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded …
F Baldanti, MR Underwood, SC Stanat… - Journal of …, 1996 - Am Soc Microbiol
Three human cytomegalovirus (HCMV) strains (VR4760, VR4955, and VR5120) showing
double resistance to ganciclovir (GCV) and foscarnet (PFA) were isolated from three patients …
double resistance to ganciclovir (GCV) and foscarnet (PFA) were isolated from three patients …
Rapid screening for resistance to ganciclovir and foscarnet of primary isolates of human cytomegalovirus from culture-positive blood samples
G Gerna, A Sarasini, E Percivalle… - Journal of clinical …, 1995 - Am Soc Microbiol
A rapid screening assay for the detection of resistance to ganciclovir and foscarnet of
primary isolates of human cytomegalovirus from culture-positive blood samples was …
primary isolates of human cytomegalovirus from culture-positive blood samples was …
Resistance of human cytomegalovirus to antiviral drugs
A Erice - Clinical Microbiology Reviews, 1999 - Am Soc Microbiol
Resistance of cytomegalovirus (CMV) to antiviral agents is a well-recognized phenomenon
that has been observed in the laboratory and in the clinical setting. Infections caused by …
that has been observed in the laboratory and in the clinical setting. Infections caused by …
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance
S Chou, RC Miner, WL Drew - The Journal of infectious diseases, 2000 - academic.oup.com
A patient with AIDS and cytomegalovirus (CMV) retinitis received ganciclovir and foscarnet
for 20 and 5 months, respectively, with evidence of periodic disease progression. After this …
for 20 and 5 months, respectively, with evidence of periodic disease progression. After this …
Polyradiculopathy associated with ganciclovir-resistant cytomegalovirus in an AIDS patient: phenotypic and genotypic characterization of sequential virus isolates
IL Smith, M Shinkai, WR Freeman… - Journal of Infectious …, 1996 - academic.oup.com
To investigate the role of antiviral drug resistance in cytomegalovirus (CMV) disease
progression, CMV cultured from an AIDS patient who developed progressive CMV disease …
progression, CMV cultured from an AIDS patient who developed progressive CMV disease …
Emergence of multiple drug-resistant human cytomegalovirus variants in 2 patients with human immunodeficiency virus infection unresponsive to highly active …
F Baldanti, S Paolucci, A Parisi… - Clinical infectious …, 2002 - academic.oup.com
In 2 patients infected with human immunodeficiency virus (HIV), highly active antiretroviral
therapy was unable to suppress HIV replication as a result of the emergence of drug …
therapy was unable to suppress HIV replication as a result of the emergence of drug …