The Existing Evidence Traditionally, LVNC has been diagnosed according to criteria applied
to transthoracic echocardiogram results, which focus on the ratio of noncompacted to …

The genetic etiology and heritability of left ventricular noncompaction (LVNC) in adults is
unclear. This study sought to assess the value of genetic testing in adults with LVNC. Adults …

Presently, although controversial, LVNC is considered to be primarily a genetic condition. It
frequently manifests as a monogenic disease, exhibiting various forms of inheritance with …

scribes a myocardial phenotype resulting from different, incompletely understood, and
undefined genetic and pathophysiological mechanisms (1). In a recent retrospective Dutch …

Background—Left ventricular noncompaction (LVNC) can occur in isolation or can co-occur
with a cardiomyopathy phenotype or cardiovascular malformation. The yield of …

2 Hershberger et al Left Ventricular Noncompaction 1480 individuals from the UK-Canadian
TASCFORCE study (Tayside Screening for Cardiac Events), also identified LVNC as a …

Background—Left ventricular noncompaction (LVNC) is a genetically and phenotypically
heterogeneous disease and, although increasingly recognized in clinical practice, there is a …

Whether left ventricular noncompaction (LVNC) is a distinct cardiomyopathy or a
morphologic trait shared by different cardiomyopathies remains controversial. Current …

Background—Left ventricular (LV) noncompaction (LVNC) is a distinct cardiomyopathy
featuring a thickened bilayered LV wall consisting of a thick endocardial layer with …

Background: There is considerable overlap between left ventricular noncompaction (LVNC)
and other cardiomyopathies. LVNC has been reported in up to 40% of the general …