In this study, we aimed to demonstrate that a significant increase in dietary iron intake
disrupts the regulation of copper availability, ultimately leading to systemic copper …

Copper is an essential trace element in human body and plays an important role in
maintaining health in humans. Copper is involved in various metabolic pathways in human …

Alcoholic liver disease (ALD) arises due to excess use of alcohol for a long period of time
and ranges from hepatic steatosis to steatohepatitis, cirrhosis, and even hepatocellular …

Objective: Animal models and studies in adults have demonstrated that copper restriction
increases severity of liver injury in nonalcoholic fatty liver disease (NAFLD). This has not …

The pathogenesis of non-alcoholic fatty liver disease (NAFLD), the most prevalent chronic
liver disease, is associated with zinc deficiency. Previous studies show zinc …

Copper toxicity in the liver is mediated by free-radical generation, resulting in oxidative
stress. To prevent toxic accumulation of copper, liver cells adapt to high copper levels. Here …

Aim: We were interested in understanding whether the chelating activity of Oleuropein (Ole)
was able to improve the copper accumulation and the related pro-oxidant and glycative …

1. Conclusions Although the authors are to be congratulated on their hard work, the
association between copper deficiency and NAFLD still seems unclear. Copper deficiency …

The interactions of different dietary doses of copper with fructose contribute to the
development of metabolic dysfunction-associated steatotic liver disease (MASLD) via the gut …

Background COMMD1-deficient dogs progressively develop copper-induced chronic
hepatitis. Since high copper leads to oxidative damage, we measured copper metabolism …