Crosstalk between ion channels and small GTPases is critical during homeostasis and
disease, but little is known about the structural underpinnings of these interactions. TRPV4 is …

Crosstalk between ion channels and small GTPases is critical during homeostasis and
disease, but little is known about the structural underpinnings of these interactions. TRPV4 is …

The interplay between ion channels and small GTPases is crucial during homeostasis and
disease, yet the structural basis remains elusive. TRPV4, a versatile calcium-permeable …

The transient receptor potential vanilloid type 4 (TRPV4), which belongs to the TRP
(transient receptor potential) ion channel family, is expressed in various cell types …

Transient receptor potential (TRP) channel TRPV4 is a polymodal cellular sensor that
responds to moderate heat, cell swelling, shear stress, and small-molecule ligands. It is …

Transient receptor potential (TRP) channel TRPV4 is a polymodal cellular sensor that
responds to moderate heat, cell swelling, shear stress, and small-molecule ligands. It is …

Transient receptor potential vanilloid (TRPV) channels are a family of polymodal cation
channels that have diverse functions across human physiology. As such, they are essential …

Widely recognized in channelopathy spectrum disorders, dominant mutations in TRPV4
(transient receptor potential vanilloid 4) have been found in both nervous system and …

Calcium homeostasis is a highly regulated process in the body. Transient receptor potential
vanilloid 5 (TRPV5) is a calcium selective ion channel that is responsible for the regulation …

The human transient receptor potential vanilloid 4 (hTRPV4) ion channel plays a critical role
in a variety of biological processes. Whilst the activation of hTRPV4 gating properties has …