Advances in the fields of biotechnology and biomaterials offer the orthopaedic surgeon the
exciting possibility of repair or regeneration of tissue lost to injury, disease, or aging. The …

Ligament and tendon injuries are common clinical problems. Healing of these tissues
occurs, but their properties do not return to normal. This predisposes to recurrent injuries …

Sports injuries usually involve tissues that display a limited capacity for healing. The
treatment of sports injuries has improved over the past 10 to 20 years through sophisticated …

Background Treatment of large Achilles tendon defects is technically demanding. Tissue
engineering is an option. We constructed a collagen-based artificial tendon, covered it with a …

Tendons connect muscles to bones, and serve as the transmitters of force that allow all the
movements of the body. Tenocytes are the basic cellular units of tendons, and produce the …

Tendon rupture is a common injury. Inadequate endogenous repair often leaves patients
symptomatic, with tendons susceptible to re-rupture. Administration of certain growth factors …

Mutilating injuries of the hand and upper extremity result in tendon losses too great to be
replaced by autologous grafts. The goal of this study was to use tissue engineering …

As dense connective tissues connecting bone to muscle and bone to bone, respectively,
tendon and ligament (T/L) arise from the somitic mesoderm, originating in a recently …

Traumatic knee injuries frequently involve the disruption of multiple ligaments, such as a
complete tear of the medial collateral ligament (MCL) together with a rupture of the anterior …