Nutraceuticals and mitochondrial oxidative stress: bridging the gap in the management of bronchial asthma
Asthma is a chronic inflammatory disease primarily characterized by inflammation and
reversible bronchoconstriction. It is currently one of the leading causes of morbidity and …
reversible bronchoconstriction. It is currently one of the leading causes of morbidity and …
Mitochondrial dysfunction and oxidative stress in asthma: implications for mitochondria-targeted antioxidant therapeutics
PH Reddy - Pharmaceuticals, 2011 - mdpi.com
Asthma is a complex, inflammatory disorder characterized by airflow obstruction of variable
degrees, bronchial hyper-responsiveness, and airway inflammation. Asthma is caused by …
degrees, bronchial hyper-responsiveness, and airway inflammation. Asthma is caused by …
Mitochondrial function in allergic disease
Abstract Purpose of the Review The connections between allergy, asthma and metabolic
syndrome are becoming increasingly clear. Recent research suggests a unifying …
syndrome are becoming increasingly clear. Recent research suggests a unifying …
Mitochondria signaling pathways in allergic asthma
L Qian, E Mehrabi Nasab, SM Athari… - Journal of …, 2022 - journals.sagepub.com
Mitochondria, as the powerhouse organelle of cells, are greatly involved in regulating cell
signaling pathways, including those related to the innate and acquired immune systems …
signaling pathways, including those related to the innate and acquired immune systems …
Airway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into blood
A Nadeem, N Siddiqui, NO Alharbi… - Pulmonary pharmacology …, 2014 - Elsevier
Asthma is characterized by repeated episodes of airway obstruction and an ongoing cycle of
airway inflammation. Reactive oxygen species (ROS) produced by inflammatory cells in the …
airway inflammation. Reactive oxygen species (ROS) produced by inflammatory cells in the …
[HTML][HTML] Advance of antioxidants in asthma treatment
LY Zhu, ZH Ni, XM Luo, XB Wang - World Journal of Respirology, 2017 - wjgnet.com
Asthma is an allergic disease, characterized as a recurrent airflow limitation, airway
hyperreactivity, and chronic inflammation, involving a variety of cells and cytokines. Reactive …
hyperreactivity, and chronic inflammation, involving a variety of cells and cytokines. Reactive …
Targeting the mitochondria in chronic respiratory diseases
DK Chellappan, KR Paudel, NW Tan, KS Cheong… - Mitochondrion, 2022 - Elsevier
Mitochondria are one of the basic essential components for eukaryotic life survival. It is also
the source of respiratory ATP. Recently published studies have demonstrated that …
the source of respiratory ATP. Recently published studies have demonstrated that …
Oxidant—antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options
A Nadeem, A Masood… - Therapeutic advances in …, 2008 - journals.sagepub.com
Prevalence of asthma has increased considerably in recent decades throughout the world
especially in developed countries. Airway inflammation is thought to be prime cause for …
especially in developed countries. Airway inflammation is thought to be prime cause for …
Mitochondrial dysfunctions associated with chronic respiratory diseases and their targeted therapies: an update
Mitochondria are autonomous cellular organelles present in most of the eukaryotic cells and
are primarily responsible for cellular metabolism. Their structure essentially consists of four …
are primarily responsible for cellular metabolism. Their structure essentially consists of four …
Review–nutraceuticals can target asthmatic bronchoconstriction: NADPH oxidase-dependent oxidative stress, RhoA and calcium dynamics
MF McCarty, JJ DiNicolantonio… - Journal of Asthma and …, 2021 - Taylor & Francis
Activation of various isoforms of NADPH oxidase contributes to the pathogenesis of asthma
at multiple levels: promoting hypercontractility, hypertrophy, and proliferation of airway …
at multiple levels: promoting hypercontractility, hypertrophy, and proliferation of airway …