cAMP-elevating agents such as forskolin and vasoactive intestinal peptide induce liquid
secretion by tracheobronchial submucosal glands. This pathway is thought to be CFTR …

Previous studies demonstrated that ACh-induced liquid secretion by porcine bronchi is
driven by active Cl− and H CO 3− secretion. The present study was undertaken to determine …

Airway submucosal glands are important sites of cystic fibrosis transmembrane conductance
regulator (CFTR) chloride (Cl−) channel expression and fluid secretion in the airway …

The present study was undertaken to identify and determine the mechanism of
noncholinergic pathways for the induction of liquid secretion across airway epithelium …

Airway submucosal glands have been proposed as a primary site for initiating and
sustaining airway disease in cystic fibrosis (CF). However, it has been difficult to define the …

Cystic fibrosis (CF), which is caused by mutations in CFTR, affects many tissues, including
the lung. Submucosal gland serous acinar cells are primary sites of fluid secretion and …

1 There is evidence that defective submucosal gland secretion contributes to the airway
pathology of cystic fibrosis (CF). Using a capacitance probe technique, we have compared …

Inhaled hypertonic saline (HTS) treatment is used to improve lung health in patients with
cystic fibrosis (CF). The current consensus is that the treatment generates an osmotic …

Tracheal submucosal glands are of great relative importance in the secretion of chloride and
water to the airway lumen. This study aimed to examine whether the cystic fibrosis …

Active Na+ transport by alveolar epithelial cells has been demonstrated to contribute
significantly to alveolar fluid clearance. However, the contribution of transepithelial Cl …