Insights into the Mechanisms of Protective Immunity against Cryptococcus neoformans Infection Using a Mouse Model of Pulmonary Cryptococcosis
KL Wozniak, S Ravi, S Macias, ML Young… - PloS one, 2009 - journals.plos.org
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …
pneumonia and meningoencephalitis in immune compromised individuals. Previous studies …
Induction of Broad-Spectrum Protective Immunity against Disparate Cryptococcus Serotypes
Cryptococcosis is a fungal disease caused by multiple Cryptococcus serotypes; particularly
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …
C. neoformans (serotypes A and D) and C. gattii (serotypes B and C). To date, there is no …
Cytokine and chemokine expression in the central nervous system associated with protective cell-mediated immunity against Cryptococcus neoformans
WC Uicker, HA Doyle, JP McCracken… - Medical …, 2005 - academic.oup.com
Cryptococcus neoformans is a yeast that causes cryptococcosis, a life-threatening disease
that develops following inhalation and dissemination of the organisms. C. neoformans has a …
that develops following inhalation and dissemination of the organisms. C. neoformans has a …
Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain
FL Wormley Jr, GM Cox, JR Perfect - Microbial pathogenesis, 2005 - Elsevier
Cryptococcus neoformans is an opportunistic fungal pathogen that threatens individuals with
impaired cell-mediated immunity (CMI). Presently, there are no standardized vaccines …
impaired cell-mediated immunity (CMI). Presently, there are no standardized vaccines …
[HTML][HTML] Protective immunity against pulmonary cryptococcosis is associated with STAT1-mediated classical macrophage activation
SE Hardison, G Herrera, ML Young… - The Journal of …, 2012 - journals.aai.org
Experimental pulmonary Cryptococcus neoformans infection in BALB/c mice is associated
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …
with polarized Th2-type cytokine production, alternative macrophage activation, and severe …
A proteomic‐based approach for the identification of immunodominant Cryptococcus neoformans proteins
M Young, S Macias, D Thomas, FL Wormley Jr - Proteomics, 2009 - Wiley Online Library
Cryptococcus neoformans is an opportunistic fungal pathogen that can cause life‐
threatening meningoencephalitis in immune compromised patients. Previous, studies in our …
threatening meningoencephalitis in immune compromised patients. Previous, studies in our …
Protective immunity against experimental pulmonary cryptococcosis in T cell-depleted mice
KL Wozniak, ML Young… - Clinical and Vaccine …, 2011 - Am Soc Microbiol
Individuals with defects in T cell-mediated immunity (CMI) are highly susceptible to infection
with Cryptococcus neoformans. The purpose of these studies was to determine if protection …
with Cryptococcus neoformans. The purpose of these studies was to determine if protection …
[HTML][HTML] Animal models of Cryptococcus neoformans in identifying immune parameters associated with primary infection and reactivation of latent infection
TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …
Protection against Cryptococcosis by Using a Murine Gamma Interferon-Producing Cryptococcus neoformans Strain
FL Wormley Jr, JR Perfect, C Steele… - Infection and …, 2007 - Am Soc Microbiol
We evaluated cell-mediated immune (CMI) responses in mice given a pulmonary infection
with a Cryptococcus neoformans strain engineered to produce the Th1-type cytokine gamma …
with a Cryptococcus neoformans strain engineered to produce the Th1-type cytokine gamma …
[HTML][HTML] Protective immunity against Cryptococcus neoformans infection
J Schop - McGill Journal of Medicine: MJM, 2007 - ncbi.nlm.nih.gov
Cryptococcus neoformans, the etiological agent of cryptococcosis, is an occasional
opportunistic fungal pathogen of immune competent individuals. However, it is a relatively …
opportunistic fungal pathogen of immune competent individuals. However, it is a relatively …