“Streptococcal inhibitor of complement”(SIC) and “distantly related to SIC”(DRS) are related
virulence factors secreted by M1 and M12 strains of GAS, respectively. The human mucosal …

Background: Intermedilysin (ILY) is a human specific cytolysin secreted by Streptococcus
intermedius. In the present study, we performed molecular modeling of ILY and cholesterol …

Abstract Background Salmonella enterica serovar Typhi (S. Typhi) stg operon, encoding a
chaperone/usher fimbria (CU), contributes to an increased adherence to human epithelial …

Bacterial attachment to host tissue is considered to be a crucial primary step in pathogen
infection. Previous studies have shown that Streptococcus defectivus adheres specifically to …

Bacteria utilize quorum-sensing communication to organize their behavior by monitoring the
concentration of bacterial signals, referred to as autoinducers (AIs). The widespread …

Serotype M1 Streptococcus pyogenes is a major human pathogen associated with severe
invasive diseases causing high morbidity and mortality. In a substantial number of cases …

The role of cell glycosaminoglycans (GAG) on adherence and internalization of
Streptococcus uberis to bovine mammary epithelial cells was evaluated by adherence …

The ability to enter into (invade) mammalian cells is an essential virulence determinant of
many pathogenic bacteria and intracellular parasites. These organisms are internalized by …

Streptococcus equi subsp. zooepidemicus (S. zooepidemicus) is an opportunistic pathogen
of several species including humans. S. zooepidemicus is found on mucus membranes of …

Cell ablation is a powerful tool for studying cell lineage and/or function; however, current cell-
ablation models have limitations. Intermedilysin (ILY), a cytolytic pore-forming toxin that is …