We have characterized a novel surface protein from urea extract of whole cells of group A
Streptococcus pyogenes (GAS). A major protein band (35kD) was found to hybridize with …

Background: The contact system, a branch of innate immunity, is also exploited by bacterial
pathogens. Results: Group G streptococcal surface proteins activate the system and protect …

Streptococcus suis is an important pathogen of pigs causing arthritis, pneumonia and
meningitis and is an occupational disease of farmers and those in the meat industry. As with …

The invasin protein of Yersinia pseudotuberculosis binds to integrin receptors on
mammalian cells and promotes cellular penetration. We demonstrate here that the cell …

By interacting with components of the human host, including extracellular matrix (ECM)
proteins, Streptococcus pneumoniae has evolved various strategies for colonization. Here …

Studies in our laboratory have identified two fimbria-associated adhesins, FimA and Fap1, of
Streptococcus parasanguis FW213. In this study, we isolated and sequenced DNA …

Abstract Streptococcus suis 2 (SS2) is a zoonotic pathogen that can participate in biofilm
formation to survive in hostile environments. In this study, virulent SS2 strains HA9801 and …

Abstract The autoinducer-2 signal (AI-2) produced by several Gram-positive and Gram-
negative bacteria mediates interspecies communication. In this study we were able to …

In response to bacterial infection epithelial cells up-regulate expression and secretion of
proinflammatory cytokines. Previous work from our laboratory showed that basolateral …

Streptococcus uberis is commonly found in the environment and in association with various
bovine body sites and is a major cause of bovine mastitis. Moreover, S. uberis is known to …