[HTML][HTML] Homeostatic control of spontaneous activity in the developing auditory system

TA Babola, S Li, A Gribizis, BJ Lee, JB Issa, HC Wang… - Neuron, 2018 - cell.com
Neurons in the developing auditory system exhibit spontaneous bursts of activity before
hearing onset. How this intrinsically generated activity influences development remains …

Spontaneous activity in the developing auditory system

HC Wang, DE Bergles - Cell and tissue research, 2015 - Springer
Spontaneous electrical activity is a common feature of sensory systems during early
development. This sensory-independent neuronal activity has been implicated in promoting …

Purinergic signaling controls spontaneous activity in the auditory system throughout early development

TA Babola, S Li, Z Wang, CJ Kersbergen… - Journal of …, 2021 - Soc Neuroscience
Spontaneous bursts of electrical activity in the developing auditory system arise within the
cochlea before hearing onset and propagate through future sound-processing circuits of the …

Developmental regulation of spontaneous activity in the Mammalian cochlea

NX Tritsch, DE Bergles - Journal of Neuroscience, 2010 - Soc Neuroscience
Neurons in the developing auditory system fire bursts of action potentials before the onset of
hearing. This spontaneous activity promotes the survival and maturation of auditory neurons …

The origin of spontaneous activity in the developing auditory system

NX Tritsch, E Yi, JE Gale, E Glowatzki, DE Bergles - Nature, 2007 - nature.com
Spontaneous activity in the developing auditory system is required for neuronal survival as
well as the refinement and maintenance of tonotopic maps in the brain. However, the …

Conductive hearing loss disrupts synaptic and spike adaptation in developing auditory cortex

H Xu, VC Kotak, DH Sanes - Journal of Neuroscience, 2007 - Soc Neuroscience
Although sensorineural hearing loss (SNHL) is known to compromise central auditory
structure and function, the impact of milder forms of hearing loss on cellular neurophysiology …

Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells

SL Johnson, T Eckrich, S Kuhn, V Zampini… - Nature …, 2011 - nature.com
Spontaneous action potential activity is crucial for mammalian sensory system development.
In the auditory system, patterned firing activity has been observed in immature spiral …

Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity

SL Johnson, S Kuhn, C Franz… - Proceedings of the …, 2013 - National Acad Sciences
The development of neural circuits relies on spontaneous electrical activity that occurs
during immature stages of development. In the developing mammalian auditory system …

Auditory neurons make stereotyped wiring decisions before maturation of their targets

EJ Koundakjian, JL Appler… - Journal of …, 2007 - Soc Neuroscience
Cochlear ganglion neurons communicate sound information from cochlear hair cells to
auditory brainstem neurons through precisely wired circuits. Understanding auditory circuit …

[HTML][HTML] The precise temporal pattern of prehearing spontaneous activity is necessary for tonotopic map refinement

A Clause, G Kim, M Sonntag, CJC Weisz, DE Vetter… - Neuron, 2014 - cell.com
Patterned spontaneous activity is a hallmark of developing sensory systems. In the auditory
system, rhythmic bursts of spontaneous activity are generated in cochlear hair cells and …