[HTML][HTML] Homeostatic control of spontaneous activity in the developing auditory system
Neurons in the developing auditory system exhibit spontaneous bursts of activity before
hearing onset. How this intrinsically generated activity influences development remains …
hearing onset. How this intrinsically generated activity influences development remains …
Spontaneous activity in the developing auditory system
HC Wang, DE Bergles - Cell and tissue research, 2015 - Springer
Spontaneous electrical activity is a common feature of sensory systems during early
development. This sensory-independent neuronal activity has been implicated in promoting …
development. This sensory-independent neuronal activity has been implicated in promoting …
Purinergic signaling controls spontaneous activity in the auditory system throughout early development
Spontaneous bursts of electrical activity in the developing auditory system arise within the
cochlea before hearing onset and propagate through future sound-processing circuits of the …
cochlea before hearing onset and propagate through future sound-processing circuits of the …
Developmental regulation of spontaneous activity in the Mammalian cochlea
NX Tritsch, DE Bergles - Journal of Neuroscience, 2010 - Soc Neuroscience
Neurons in the developing auditory system fire bursts of action potentials before the onset of
hearing. This spontaneous activity promotes the survival and maturation of auditory neurons …
hearing. This spontaneous activity promotes the survival and maturation of auditory neurons …
The origin of spontaneous activity in the developing auditory system
Spontaneous activity in the developing auditory system is required for neuronal survival as
well as the refinement and maintenance of tonotopic maps in the brain. However, the …
well as the refinement and maintenance of tonotopic maps in the brain. However, the …
Conductive hearing loss disrupts synaptic and spike adaptation in developing auditory cortex
H Xu, VC Kotak, DH Sanes - Journal of Neuroscience, 2007 - Soc Neuroscience
Although sensorineural hearing loss (SNHL) is known to compromise central auditory
structure and function, the impact of milder forms of hearing loss on cellular neurophysiology …
structure and function, the impact of milder forms of hearing loss on cellular neurophysiology …
Position-dependent patterning of spontaneous action potentials in immature cochlear inner hair cells
SL Johnson, T Eckrich, S Kuhn, V Zampini… - Nature …, 2011 - nature.com
Spontaneous action potential activity is crucial for mammalian sensory system development.
In the auditory system, patterned firing activity has been observed in immature spiral …
In the auditory system, patterned firing activity has been observed in immature spiral …
Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity
SL Johnson, S Kuhn, C Franz… - Proceedings of the …, 2013 - National Acad Sciences
The development of neural circuits relies on spontaneous electrical activity that occurs
during immature stages of development. In the developing mammalian auditory system …
during immature stages of development. In the developing mammalian auditory system …
Auditory neurons make stereotyped wiring decisions before maturation of their targets
EJ Koundakjian, JL Appler… - Journal of …, 2007 - Soc Neuroscience
Cochlear ganglion neurons communicate sound information from cochlear hair cells to
auditory brainstem neurons through precisely wired circuits. Understanding auditory circuit …
auditory brainstem neurons through precisely wired circuits. Understanding auditory circuit …
[HTML][HTML] The precise temporal pattern of prehearing spontaneous activity is necessary for tonotopic map refinement
Patterned spontaneous activity is a hallmark of developing sensory systems. In the auditory
system, rhythmic bursts of spontaneous activity are generated in cochlear hair cells and …
system, rhythmic bursts of spontaneous activity are generated in cochlear hair cells and …
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