Fractional factorial design study for the extraction of cannabinoids from CBD-dominant cannabis flowers by supercritical carbon dioxide

S Qamar, YJM Torres, HS Parekh, JR Falconer - Processes, 2022 - mdpi.com
The optimization of the supercritical fluid extraction (SFE) of cannabinoids, using
supercritical carbon dioxide (scCO2), was investigated in a fractional factorial design study …

Effects of ethanol on the supercritical carbon dioxide extraction of cannabinoids from near equimolar (THC and CBD balanced) cannabis flower

S Qamar, YJM Torres, HS Parekh, JR Falconer - Separations, 2021 - mdpi.com
In this study, supercritical carbon dioxide (scCO2) extractions of cannabinoids were
conducted at four different densities (231, 590, 818, and 911 kg/m3) using ethanol (5% w/v) …

Supercritical extraction strategies using CO2 and ethanol to obtain cannabinoid compounds from Cannabis hybrid flowers

DR Grijó, IAV Osorio, L Cardozo-Filho - Journal of CO2 Utilization, 2019 - Elsevier
The cannabidiol (CBD) and Δ 9-tetrahydrocannabinol (Δ 9-THC) are the two main
cannabinoids with medicinal potential. However, these substances are found in low …

Development and optimization of supercritical fluid extraction setup leading to quantification of 11 cannabinoids derived from medicinal cannabis

S Qamar, YJ Manrique, HS Parekh, JR Falconer - Biology, 2021 - mdpi.com
Simple Summary This study describes the design and development of setup for the
extraction of cannabis strain 1 (Cannabidiol dominant) using supercritical carbon dioxide …

Supercritical carbon dioxide extraction of cannabinoids from Cannabis sativa L.

LJ Rovetto, NV Aieta - The Journal of Supercritical Fluids, 2017 - Elsevier
Cannabis sativa L. extracts with high concentration of Δ 9-tetrahydrocannabinolic acid
(THCA) and Δ 9-tetrahydrocannabinol (THC) were obtained by supercritical carbon dioxide …

Supercritical fluid extraction of cannabinoids (THC and CBD) from four different strains of cannabis grown in different regions

U Karğılı, E Aytaç - The Journal of Supercritical Fluids, 2022 - Elsevier
The aim of this study is to investigate the cannabinoid content of different types of cannabis
plants grown in different climatic regions under different supercritical extraction conditions …

Optimization of supercritical carbon dioxide fluid extraction of medicinal cannabis from Quebec

H Boumghar, M Sarrazin, X Banquy, DC Boffito… - Processes, 2023 - mdpi.com
Research on cannabis oil has evolved to encompass the pharmaceutical industry for the
therapeutic potential of the active compounds for pathologies such as Alzheimer, auto …

Utilisation of design of experiments approach to optimise supercritical fluid extraction of medicinal cannabis

S Rochfort, A Isbel, V Ezernieks, A Elkins, D Vincent… - Scientific reports, 2020 - nature.com
Carbon dioxide supercritical fluid extraction (CO2 SFE) is a clean and cost-effective method
of extracting cannabinoids from cannabis. Using design of experiment methodologies an …

Valorization of Wild-Type Cannabis indica by Supercritical CO2 Extraction and Insights into the Utilization of Raffinate Biomass

F Pattnaik, N Hans, BR Patra, S Nanda, V Kumar… - Molecules, 2022 - mdpi.com
Supercritical CO2 extraction (SCCO2) extraction of cannabis oil from Indian cannabis
(Cannabis indica) leaves was optimized through a central composite design using CO2 …

Supercritical CO2 extraction of hemp flowers: A systematic study to produce terpene-rich and terpene-depleted cannabidiol fractions

SV Luca, T Kittl, M Minceva - Industrial Crops and Products, 2022 - Elsevier
Despite their high-added value, terpenes currently have limited exploitation in the hemp
industry, often ending up in the sidestream of cannabidiol extraction and/or purification. In …