Cu-Chelated polydopamine nanoparticles as a photothermal medium and “immunogenic cell death” inducer for combined tumor therapy

N Xu, A Hu, X Pu, J Wang, X Liao, Z Huang… - Journal of Materials …, 2022 - pubs.rsc.org
Chemodynamic therapy (CDT) and photothermal therapy (PTT) have been powerful
technologies for tumor ablation. However, how to realize efficient CDT and PTT synergetic …

Spatial targeting of tumor-associated macrophages and tumor cells with a pH-sensitive cluster nanocarrier for cancer chemoimmunotherapy

S Shen, HJ Li, KG Chen, YC Wang, XZ Yang… - Nano Letters, 2017 - ACS Publications
Chemoimmunotherapy, which combines chemotherapeutics with immune-modulating
agents, represents an appealing approach for improving cancer therapy. To optimize its …

Converting primary tumor towards an in situ STING-activating vaccine via a biomimetic nanoplatform against recurrent and metastatic tumors

X Yang, Y Yang, J Bian, J Wei, Z Wang, Z Zhou, Z Li… - Nano Today, 2021 - Elsevier
Currently, vaccine is a promising tumor prevention modality in cancer therapy. However, it is
hard to elicit robust antitumor immunity in patients already afflicted with tumor, inspiring a …

Liquid metal nanoplatform based autologous cancer vaccines

D Wang, Z Yu, Y Qi, K Hu, T Zhou, J Liu, W Rao - ACS nano, 2023 - ACS Publications
Therapeutic cancer vaccines have been vigorously sought to bolster host adaptive immunity
against metastatic cancers, but tumor heterogeneity, ineffective antigen utilization, and …

Nanocarrier-mediated chemo-immunotherapy arrested cancer progression and induced tumor dormancy in desmoplastic melanoma

Q Liu, F Chen, L Hou, L Shen, X Zhang, D Wang… - ACS …, 2018 - ACS Publications
In desmoplastic melanoma, tumor cells and tumor-associated fibroblasts are the major
dominators playing a critical role in the fibrosis morphology as well as the …

Paraptosis inducer to effectively trigger immunogenic cell death for metastatic tumor immunotherapy with IDO inhibition

RR Zheng, LP Zhao, CY Huang, H Cheng, N Yang… - ACS …, 2023 - ACS Publications
Paraptosis is characterized by the extensive vacuolization of endoplasmic reticulum (ER)
and mitochondria, which will cause the release of damage-associated molecular patterns to …

Reprogramming Tumor‐Associated Macrophages via ROS‐Mediated Novel Mechanism of Ultra‐Small Cu2−xSe Nanoparticles to Enhance Anti‐Tumor Immunity

Y Zheng, Y Han, T Wang, H Liu, Q Sun… - Advanced Functional …, 2022 - Wiley Online Library
Reprogramming tumor‐associated macrophages (TAMs) from tumor‐supportive M2
phenotype to anti‐tumor M1 phenotype holds great promise in tumor immunotherapy …

A nano “immune‐guide” recruiting lymphocytes and modulating the ratio of macrophages from different origins to enhance cancer immunotherapy

W Sun, J Yang, M Hou, S Xie, L Xiong… - Advanced Functional …, 2021 - Wiley Online Library
Artificially modulating the type, density, and location of immune cells within the tumor
microenvironment can suppress tumor growth and efficiently promote current …

Multifunctional redox-responsive nanoplatform with dual activation of macrophages and T cells for antitumor immunotherapy

W Zhang, X Liu, S Cao, Q Zhang, X Chen, W Luo… - ACS …, 2023 - ACS Publications
High expression of programmed death ligand 1 (PD-L1) and strong immune evasion ability
of the tumor microenvironment (TME) are maintained through mutual regulation between …

MnO2-melittin nanoparticles serve as an effective anti-tumor immunotherapy by enhancing systemic immune response

S Tang, L Zhou, H He, L Cui, Z Ren, Y Tai, Z Xie, Y Cao… - Biomaterials, 2022 - Elsevier
Cancer vaccines are viewed as a promising immunotherapy to eradicate malignant tumors
and aim to elicit the patients' own tumor-specific immune response against tumor cells …