Although anti-PD-1 immunotherapy is widely used to treat melanoma, its efficacy still has to
be improved. In this work, we present a therapeutic method that combines immunotherapy …

A major challenge for traditional cancer therapy, including surgical resection,
chemoradiotherapy, and immunotherapy, is how to induce tumor cell death and leverage the …

Immunotherapy as an alternative treatment strategy for B-cell lymphoma is undesirable
because of tumor heterogeneity and immune surveillance. Spermidine (SPM), as a regulator …

Hypoxia is a major obstacle towards successful cancer treatment, due to the hypoxia-
mediated resistance to radiotherapy and chemotherapy, as well as immunosuppression …

Chemodynamic therapy (CDT) efficacy has been limited by the poor penetration ability of
large nanoparticles (NPs) and the antioxidant activity of tumors, especially high heme …

Low persistence, metabolic dysfunction in microenvironment, and tumor‐derived
immunosuppression of Natural killer (NK) cells in patients are greatly limited the successful …

The checkpoint blockade‐based immunotherapy has recently emerged as a promising
approach for tumor treatment, but its clinical implementation has been impeded by poor …

Melanoma is a malignant skin cancer that is prone to metastasis in the early stage and has a
poor prognosis. Immunomodulatory therapy for melanoma has been a hot research topic in …

Metal‐based nanomaterials have attracted broad attention recently due to their unique
biological physical and chemical properties after entering tumor cells, namely biological …

Pyroptosis, as a novel mode of cell death, has been proven to have impressive antitumor
effects. Dying cells undergoing pyroptosis can elicit antitumor immunity by the release of …