Galanin receptors and ligands
KEB Webling, J Runesson, T Bartfai… - Frontiers in …, 2012 - frontiersin.org
The neuropeptide galanin was first discovered 30 years ago. Today, the galanin family
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …
consists of galanin, galanin-like peptide (GALP), galanin-message associated peptide …
In vivo and in vitro effects of peripheral galanin on nociceptive transmission in naive and neuropathic states
SJL Flatters, AJ Fox, AH Dickenson - Neuroscience, 2003 - Elsevier
Galanin is widely distributed in the nervous system and is consistently upregulated in both
dorsal root ganglion and spinal neurones by peripheral nerve injury. This study investigates …
dorsal root ganglion and spinal neurones by peripheral nerve injury. This study investigates …
The effect of naturally occurring fragments of galanin message-associated peptide on spinal cord excitability in rats
S Andell-Jonsson, IS Xu, T Bartfai, XJ Xu… - Neuroscience …, 1997 - Elsevier
Galanin message-associated peptide (GMAP), a 60 amino acid fragment of galanin
precursor protein, is present in dorsal root ganglion cells and upon intrathecal (it) …
precursor protein, is present in dorsal root ganglion cells and upon intrathecal (it) …
The biological role of galanin in normal and neuropathic states
Publisher Summary This chapter discusses the biological role of galanin in normal and
neuropathic states. Injuries to peripheral nerves in man are associated with a range of …
neuropathic states. Injuries to peripheral nerves in man are associated with a range of …
Galanin receptor ligands
X Lu, L Lundström, U Langel, T Bartfai - Neuropeptides, 2005 - Elsevier
The three galanin receptor subtypes (GalR1–3) belong to the G protein-coupled receptor
superfamily. The widespread distribution of galanin and its receptors in the CNS and PNS …
superfamily. The widespread distribution of galanin and its receptors in the CNS and PNS …
Galanin receptor binding sites in adult rat spinal cord respond differentially to neonatal capsaicin, dorsal rhizotomy and peripheral axotomy
S Kar, R Quirion - European Journal of Neuroscience, 1994 - Wiley Online Library
The discrete distribution and possible changes in specific [125I] galanin binding sites were
evaluated in the rat spinal cord following neonatal capsaicin treatment, dorsal rhizotomy and …
evaluated in the rat spinal cord following neonatal capsaicin treatment, dorsal rhizotomy and …
Anatomy and physiology of central galanin-containing pathways
I Merchenthaler, FJ López, A Negro-Vilar - Progress in neurobiology, 1993 - Elsevier
Since the discovery of galanin (GAL) in 1983 (Tatemoto et al., 1983) numerous anatomical,
physiological and pharmacological investigations have demonstrated that the peptide is …
physiological and pharmacological investigations have demonstrated that the peptide is …
Differential galanin upregulation in dorsal root ganglia and spinal cord after graded single ligature nerve constriction of the rat sciatic nerve
MF Coronel, PR Brumovsky, T Hökfelt… - Journal of chemical …, 2008 - Elsevier
Single ligature nerve constriction (SLNC) is a newly developed animal model for the study of
neuropathic pain. SLNC of the rat sciatic nerve induces pain-related behaviors, as well as …
neuropathic pain. SLNC of the rat sciatic nerve induces pain-related behaviors, as well as …
Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain‐like behaviour
SA Hobson, FE Holmes, NCH Kerr… - Journal of …, 2006 - Wiley Online Library
Expression of the neuropeptide galanin is markedly up‐regulated within the adult dorsal root
ganglia (DRG) following peripheral nerve injury. We have previously demonstrated that …
ganglia (DRG) following peripheral nerve injury. We have previously demonstrated that …
A novel GalR2-specific peptide agonist
The galanin peptide family and its three receptors have with compelling evidence been
implicated in several high-order physiological disorders. The co-localization with other …
implicated in several high-order physiological disorders. The co-localization with other …