Exposure to carbon dioxide and helium reduces in vitro proliferation of pediatric tumor cells

AI Schmidt, M Reismann, JF Kübler, G Vieten… - Pediatric surgery …, 2006 - Springer
Background: Minimally invasive techniques are increasingly applied to children with
malignant tumors. We showed previously that CO 2 used for pneumoperitoneum modulates …

Carbon dioxide modifies the morphology and function of mesothelial cells and facilitates transepithelial neuroblastoma cell migration

Y Yu, J Kuebler, S Groos, M Metzelder… - Pediatric surgery …, 2010 - Springer
Background The response of mesothelial cells to surgical trauma and bacterial
contamination is poorly defined. We have recently shown that CO 2 pneumoperitoneum …

Pneumoperitoneum with carbon dioxide stimulates growth of malignant colonic cells

CA Jacobi, R Sabat, B Böhm, HU Zieren, HD Volk… - Surgery, 1997 - Elsevier
Background. Port-site recurrences have often been reported after laparoscopic surgery for
malignant disease, and the pathogenesis is unknown. Whether different gases used to …

Carbon dioxide, hypoxia and low pH lead to overexpression of c-myc and HMGB-1 oncogenes in neuroblastoma cells

M Reismann, F Wehrmann, N Schukfeh… - European journal of …, 2009 - thieme-connect.com
Purpose: It has been reported that CO 2 gas, used to establish a pneumoperitoneum during
laparoscopy, affects the behavior of tumor cells. The proto-oncogenes c-myc and HMGB-1 …

CO2 environment influences the growth of cultured human cancer cells dependent on insufflation pressure

CN Gutt, ZG Kim, D Hollander, T Bruttel, M Lorenz - Surgical endoscopy, 2001 - Springer
Background Experimental and clinical studies, have suggested that the CO 2
pneumoperitoneum influences the development of intraabdominal tumor dissemination and …

Influence of CO2 pneumoperitoneum during laparoscopic surgery on cancer cell growth

S Takiguchi, N Matsuura, Y Hamada, E Taniguchi… - Surgical …, 2000 - Springer
Background CO 2 pneumoperitoneum provides a new surgical environment to treat
malignant disease. The purpose of this study was to investigate the influence of CO 2 …

Laparoscopic surgery: the effects of insufflation gas on tumor-induced lethality in nude mice

J Volz, S Koster, B Schaeff, V Paolucci - American journal of obstetrics and …, 1998 - Elsevier
Objective: The aim of the study was to examine the effect of helium (group 2), carbon dioxide
(group 3), and heated carbon dioxide (group 4) pneumoperitoneum on survival in case of …

Oncological effects of insufflation with different gases and a gasless procedure in rats

M Yokoyama, H Ishida, T Okita, N Murata… - Surgical Endoscopy And …, 2003 - Springer
Background: The validity of using carbon dioxide (CO 2) pneumoperitoneum in laparoscopic
tumor surgery has not been investigated thoroughly. The oncologic effects of a gasless …

The impact of laparoscopy with carbon dioxide versus helium on immunologic function and tumor growth in a rat model

CA Jacobi, F Wenger, R Sabat, T Volk, J Ordemann… - Digestive …, 1998 - karger.com
Background: The pathogenesis of port site recurrences after laparoscopic surgery for
malignant disease is still unknown. Whether different gases used to establish …

IN VITRO INHIBITION OF TUMOUR GROWTH IN A HELIUM‐RICH ENVIRONMENT: IMPLICATIONS FOR LAPAROSCOPIC SURGERY

SJ Neuhaus, TS Ellis, MW Barrett… - Australian and New …, 1999 - Wiley Online Library
Background: The recent results of several experimental studies have suggested that tumour
implantation after laparoscopic surgery for intra‐abdominal malignancy may be partly …