Choline Phosphate-Grafted Nanozymes as Universal Extracellular Vesicle Probes for Bladder Cancer Detection

Q Li, S Zhan, X Yang, Z Zhang, N Sun, X Wang… - ACS …, 2024 - ACS Publications
Urinary extracellular vesicles (uEVs) are regarded as highly promising liquid-biopsy
biomarkers for the early diagnosis and prognosis of bladder cancer (BC). However …

Extracellular Vesicles as Potential Bladder Cancer Biomarkers: Take It or Leave It?

A Teixeira-Marques, C Lourenço, MC Oliveira… - International Journal of …, 2023 - mdpi.com
Bladder cancer (BC) is the 10th most frequently diagnosed cancer worldwide. Although
urine cytology and cystoscopy are current standards for BC diagnosis, both have limited …

Bladder cancer diagnosis and follow-up: the current status and possible role of extracellular vesicles

E Oeyen, L Hoekx, S De Wachter, M Baldewijns… - International journal of …, 2019 - mdpi.com
Diagnostic methods currently used for bladder cancer are cystoscopy and urine cytology.
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …

Urinary extracellular vesicles as potential biomarkers for urologic cancers: An overview of current methods and advances

C Lourenço, V Constâncio, R Henrique, Â Carvalho… - Cancers, 2021 - mdpi.com
Simple Summary The diagnostic and monitoring techniques used for urologic cancers
comprise a group of invasive methodologies that still lack sensitivity and specificity …

Proteomic analysis of urinary and tissue‐exudative extracellular vesicles to discover novel bladder cancer biomarkers

E Tomiyama, K Matsuzaki, K Fujita… - Cancer …, 2021 - Wiley Online Library
Proteomic analysis of urinary extracellular vesicles (EVs) is a powerful approach to discover
potential bladder cancer (BCa) biomarkers, however urine contains numerous EVs derived …

[HTML][HTML] Bladder cancer detection by urinary extracellular vesicle mRNA analysis

T Murakami, CM Yamamoto, T Akino, H Tanaka… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Objective Urinary extracellular vesicles (EV) could be promising biomarkers for urological
diseases. In this retrospective feasibility study, we conducted biomarker screening for early …

[HTML][HTML] An integrated double-filtration microfluidic device for isolation, enrichment and quantification of urinary extracellular vesicles for detection of bladder cancer

LG Liang, MQ Kong, S Zhou, YF Sheng, P Wang… - Scientific reports, 2017 - nature.com
Extracellular vesicles (EVs), including exosomes and microvesicles, are present in a variety
of bodily fluids, and the concentration of these sub-cellular vesicles and their associated …

Pre-analytical handling conditions and protein marker recovery from urine extracellular vesicles for bladder cancer diagnosis

J Lee, E Kim, J Park, S Choi, MS Lee, J Park - Plos one, 2023 - journals.plos.org
Extracellular vesicles (EVs) contain a variety of biomolecules and provide information about
the cells that produce them. EVs from cancer cells found in urine can be used as biomarkers …

[HTML][HTML] Urinary extracellular vesicles: a rising star in bladder cancer management

F Urabe, T Kimura, K Ito, Y Yamamoto… - Translational …, 2021 - ncbi.nlm.nih.gov
Clinically, the detection of bladder cancer (BCa) typically requires cystoscopy, which is
potentially harmful and sometimes accompanied by adverse effects. Thus, new biomarkers …

An integrated double-filtration microfluidic device for detection of extracellular vesicles from urine for bladder cancer diagnosis

LG Liang, YF Sheng, S Zhou, F Inci, L Li… - … Vesicles: Methods and …, 2017 - Springer
Extracellular vesicles (EVs) are present in a variety of bodily fluids and they play an
important role in cellular communications and signal transduction mechanisms. Studies …