[HTML][HTML] Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix

Y Vladic-Stjernholm, T Vladic, CS Blesson… - Reproductive Biology …, 2009 - Springer
Abstract Treatment with prostaglandin (PG)-E 2 is clinically efficient for cervical priming. The
aim of this study was to evaluate the impact of PG-E 2 on the expression of the progesterone …

Determinants of response to intracervical prostaglandin E2 for cervical ripening

R Bortolus - European Journal of Obstetrics & Gynecology and …, 1999 - Elsevier
Objective: To analyze the determinants of response to intracervical prostaglandin E2 (PGE2)
in cervical ripening. Study design: A total of 250 women with normal pregnancy, parae three …

Factors predicting labour onset in patients treated with prostaglandin E2 for cervical ripening

F Facchinetti, I Neri, AR Genazzani - European Journal of Obstetrics & …, 1995 - Elsevier
The aim of this study is the evaluation of predictive factors in the onset of labour after pre-
induction cervical ripening with prostaglandins. We enrolled 112 consecutive singleton term …

Cervical ripening after treatment with prostaglandin E2 or antiprogestin (RU486). Possible mechanisms in relation to gonadal steroids

YM Stjernholm, L Sahlin, HA Eriksson… - European Journal of …, 1999 - Elsevier
Objective: To compare the mechanisms for cervical ripening after treatment with
prostaglandin E2 or antiprogestin (RU486) to spontaneous cervical ripening, with focus on …

The expression of prostaglandin receptors EP 3 and EP 4 in human cervix in post‐term pregnancy differs between failed and successful labor induction

N Roos, CS Blesson, O Stephansson… - Acta obstetricia et …, 2014 - Wiley Online Library
Objective To investigate expression and localization of prostaglandin receptors EP 1‐4 and
FP and localization of stromal factors CTGF (connective tissue growth factor), furin …

Differential regulation of the progesterone receptor A and B in the human uterine cervix at parturition

Y Stjernholm-Vladic, H Wang, D Stygar… - Gynecological …, 2004 - Taylor & Francis
The concept of a blockade of progesterone during human pregnancy and withdrawal of this
blockade at parturition remains controversial There is no sharp fall in serum progesterone …

Cervical ripening and induction of labor by prostaglandin E2: a comparison between intracervical gel and vaginal pessary

G D'Aniello, C Bocchi, P Florio, E Ignacchiti… - The Journal of …, 2003 - Taylor & Francis
Objective: To compare the effectiveness and safety of two formulations of prostaglandin (PG)
E2 (gel and pessary) for induction of labor. Primary outcomes were cervical ripening …

Agonist-dependent downregulation of progesterone receptors in human cervical stromal fibroblasts

WE Ackerman IV, TL Summerfield… - Reproductive …, 2016 - journals.sagepub.com
Progesterone (P4) maintains uterine quiescence during the majority of pregnancy, whereas
diminished progesterone receptor (PR) expression and/or activity (ie, functional P4 …

A randomized trial of two preparations of vaginal prostaglandin for pre-induction cervical ripening

HG Murray, A Buonocore, J Hawley - Obstetrics & Gynecology, 1995 - Elsevier
OBJECTIVE: To compare two prostaglandin (PG) E2 preparations for pre-induction cervical
ripening in a randomized clinical trial. METHODS: Two milligrams of vaginal PGE2 gel was …

Cervical ripening and induction of delivery by local administration of prostaglandin E2 gel or vaginal tablets is equally effective

P Rix, P Ladehoff, AM Møller, KA Tilma… - Acta obstetricia et …, 1996 - Taylor & Francis
Background. Prostaglandin E2 for local application has been widely used for preinduction
cervical ripening in cases presenting with an unfavorable cervical state. The optimal way of …