Multimodal metagenomic analysis reveals microbial single nucleotide variants as superior biomarkers for early detection of colorectal cancer

W Gao, X Gao, L Zhu, S Gao, R Sun, Z Feng, D Wu… - Gut …, 2023 - Taylor & Francis
Microbial signatures show remarkable potentials in predicting colorectal cancer (CRC). This
study aimed to evaluate the diagnostic powers of multimodal microbial signatures, multi …

Colorectal cancer stage-specific fecal bacterial community fingerprinting of the Taiwanese population and underpinning of potential taxonomic biomarkers

CY Fang, JS Chen, BM Hsu, B Hussain, J Rathod… - Microorganisms, 2021 - mdpi.com
Despite advances in the characterization of colorectal cancer (CRC), it still faces a poor
prognosis. There is growing evidence that gut microbiota and their metabolites potentially …

Development of a colorectal cancer diagnostic model and dietary risk assessment through gut microbiome analysis

J Yang, A McDowell, EK Kim, H Seo, WH Lee… - … & molecular medicine, 2019 - nature.com
Colorectal cancer (CRC) is the third most common form of cancer and poses a critical public
health threat due to the global spread of westernized diets high in meat, cholesterol, and fat …

Leveraging fecal bacterial survey data to predict colorectal tumors

B Zhang, S Xu, W Xu, Q Chen, Z Chen, C Yan… - Frontiers in …, 2019 - frontiersin.org
Colorectal cancer (CRC) ranks second in cancer-associated mortality and third in the
incidence worldwide. Most of CRC follow adenoma-carcinoma sequence, and have more …

Leveraging sequence-based faecal microbial community survey data to identify a composite biomarker for colorectal cancer

MS Shah, TZ DeSantis, T Weinmaier, PJ McMurdie… - Gut, 2018 - gut.bmj.com
Objective Colorectal cancer (CRC) is the second leading cause of cancer-associated
mortality in the USA. The faecal microbiome may provide non-invasive biomarkers of CRC …

Progress of gut microbiome and its metabolomics in early screening of colorectal cancer

L Zhou, Z Jiang, Z Zhang, J Xing, D Wang… - Clinical and Translational …, 2023 - Springer
Gut microbes are widely considered to be closely associated with colorectal cancer (CRC)
development. The microbiota is regarded as a potential identifier of CRC, as several studies …

Gut microbiome in colorectal cancer: Clinical diagnosis and treatment

Y Liu, HCH Lau, WY Cheng, J Yu - Genomics, Proteomics & …, 2023 - academic.oup.com
Colorectal cancer (CRC) is one of the most frequently diagnosed cancers and the leading
cause of cancer-associated deaths. Epidemiological studies have shown that both genetic …

[HTML][HTML] Microbial markers in colorectal cancer detection and/or prognosis

R Villéger, A Lopès, J Veziant, J Gagnière… - World journal of …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the second leading cause of cancer worldwide. CRC is still
associated with a poor prognosis among patients with advanced disease. On the contrary …

Explainable artificial intelligence for microbiome data analysis in colorectal cancer biomarker identification

P Novielli, D Romano, M Magarelli, PD Bitonto… - Frontiers in …, 2024 - frontiersin.org
Background Colorectal cancer (CRC) is a type of tumor caused by the uncontrolled growth
of cells in the mucosa lining the last part of the intestine. Emerging evidence underscores an …

The application of high-throughput technologies for the study of microbiome and cancer

LQ Wei, IH Cheong, GH Yang, XG Li… - Frontiers in …, 2021 - frontiersin.org
Human gut microbiome research, especially gut microbiome, has been developing at a
considerable pace over the last decades, driven by a rapid technological advancement. The …