Cerebellar granule neurons express a standing outward (background) K+ current (IK, SO)
that regulates the resting membrane potential and cell excitability. As several tandem‐pore …

Background K+ channels whose subunit contains four transmembrane segments and two
pore-forming domains (4TM/2P) have been cloned recently. We studied whether 4TM/2P K+ …

Cerebellar granule neurons (CGNs) are one of the most populous cells in the mammalian
brain. They express an outwardly rectifying potassium current, termed a “standing-outward” …

TASK‐1 and TASK‐3 are functional members of the tandem‐pore K+ (K2P) channel family,
and mRNAs for both channels are expressed together in many brain regions. Although …

Tandem pore domain K+ channels represent a new family of ion channels involved in the
control of background membrane conductances. We report the structural and functional …

We have isolated from the rat cerebellum cDNA library a complementary DNA encoding a
new member of the tandem pore K+ channel family. Its amino acid sequence shares 54 …

Potassium (K) channels have a key role in the regulation of neuronal excitability. Over a
hundred different subunits encoding distinct K channel subtypes have been identified so far …

TRESK (TWIK‐related spinal cord K+ channel) is the most recently identified member of the
two‐pore‐domain potassium channel (K2P) family, the molecular source of background …

Several types of neurons within the central and peripheral somatic nervous system express
two-pore-domain potassium (K2P) channels, providing them with resting potassium …

Kv4 channels mediate most of the somatodendritic subthreshold operating A‐type current
(ISA) in neurons. This current plays essential roles in the regulation of spike timing, repetitive …