Background Although there are a number of studies comparing the currently recommended
preferred and alternative first-line (1L) antiretroviral therapy (ART) regimens on clinical …

Background. Human immunodeficiency virus type 1 (HIV-1) drug resistance may limit the
benefits of antiretroviral therapy (ART). This cohort study examined patterns of drug …

Objective: To estimate the prevalence of NRTI and NNRTI drug resistance mutations in
patients failing NNRTI-based ART in Southern Africa. Study design: We conducted a …

Background: Previous studies in HIV-positive individuals on thymidine analogue backbone
antiretroviral therapy (ART) with either nevirapine or efavirenz have suggested poorer …

We investigate mutations and correlates according to HIV-1 subtype after virological failure
(VF) of standard first-line antiretroviral therapy (ART)(non-nucleoside/nucleotide reverse …

Objectives The main objective of this analysis was to evaluate the impact of pre‐existing
drug resistance by next‐generation sequencing (NGS) on the risk of treatment failure (TF) of …

Objective: To compare WHO first-line antiretroviral therapy (ART) with nonnucleoside
reverse transcriptase inhibitors (NNRTI)-based regimen with a boosted protease inhibitor …

Objectives There is conflicting evidence on the impact of pre-existing HIV drug resistance
mutations (DRMs) in patients infected with non-B subtype virus. Methods We performed a …

Antiretroviral treatment (ART) is expanding to human immunodeficiency virus type 1 (HIV-1)–
infected persons in low-middle income countries, thanks to a public health approach. With 3 …

Background Increased access to antiretroviral therapy (ART) has resulted in rising levels of
pretreatment human immunodeficiency virus drug resistance (PDR). This is the first …