The production of immunoglobulin capable of neutralizing the infectivity of a virus represents
one of the most remarkable molecular accomplishments of the host's available immune …

Although many human sera possess potent neutralizing activities for primary HIV-1 viruses,
such activities are not efficiently induced by the current generation of vaccine candidates …

In contrast to infrequent and low-titer cross-neutralization of human immunodeficiency virus
type 1 (HIV-1) isolates by HIV-2-and simian immunodeficiency virus (SIV)-positive sera …

Human monoclonal antibodies (mAbs) to two contiguous epitopes in the V3 loop of the
human immunodeficiency virus type 1 (HIV-1) envelope have shown different effects on …

The purposes of this study were to map the targets for neutralizing Abs in the HIV-2
glycoproteins with particular emphasis on the role of the V3 region. Sera obtained from …

The third hypervariable region (V3) of the HIV-1 envelope gp120 protein contains the
principal neutralizing domain. Most neutralizing antibodies directed toward this region are …

The epitopes of the V3 domain of the human immunodeficiency virus type 1 (HIV-1) gp120
glycoprotein have complex structures consisting of linear and conformational antigenic …

Abstract mAbs specific for the V3 loop of HIV-1 are capable of neutralizing laboratory strains
of HIV-1 in vitro. In this report we use surface plasmon resonance and biosensor technology …

Although it is known that some human immune sera possess potent neutralizing activities for
primary viruses, the identity of the target epitopes mediating this neutralization is unknown …

The specific binding of antibodies to the V3 loop in sera from human immunodeficiency type
1 (HIV-1)-infected individuals was investigated. Different V3 structures were analyzed as full …