Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life
The human gut microbiome matures towards the adult composition during the first years of
life and is implicated in early immune development. Here, we investigate the effects of …
life and is implicated in early immune development. Here, we investigate the effects of …
Comparative metagenomics and population dynamics of the gut microbiota in mother and infant
PA Vaishampayan, JV Kuehl, JL Froula… - Genome biology and …, 2010 - academic.oup.com
Colonization of the gastrointestinal tract (GIT) of human infants with a suitable microbial
community is essential for numerous aspects of health, but the progression of events by …
community is essential for numerous aspects of health, but the progression of events by …
Impact of early events and lifestyle on the gut microbiota and metabolic phenotypes in young school-age children
Background The gut microbiota evolves from birth and is in early life influenced by events
such as birth mode, type of infant feeding, and maternal and infant antibiotics use. However …
such as birth mode, type of infant feeding, and maternal and infant antibiotics use. However …
Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbionts
We lack a deep understanding of genetic and metabolic attributes specializing in microbial
consortia for initial and subsequent waves of colonization of our body habitats. Here we …
consortia for initial and subsequent waves of colonization of our body habitats. Here we …
[HTML][HTML] Developmental trajectory of the healthy human gut microbiota during the first 5 years of life
J Roswall, LM Olsson, P Kovatcheva-Datchary… - Cell host & …, 2021 - cell.com
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …
established at birth. However, the succession by which different bacteria are incorporated …
Strain-resolved community genomic analysis of gut microbial colonization in a premature infant
MJ Morowitz, VJ Denef, EK Costello… - Proceedings of the …, 2011 - National Acad Sciences
The intestinal microbiome is a critical determinant of human health. Alterations in its
composition have been correlated with chronic disorders, such as obesity and inflammatory …
composition have been correlated with chronic disorders, such as obesity and inflammatory …
Deterministic transition of enterotypes shapes the infant gut microbiome at an early age
Background The succession of the gut microbiota during the first few years plays a vital role
in human development. We elucidate the characteristics and alternations of the infant gut …
in human development. We elucidate the characteristics and alternations of the infant gut …
Major faecal microbiota shifts in composition and diversity with age in a geographically restricted cohort of mothers and their children
E Avershina, O Storrø, T Øien, R Johnsen… - FEMS microbiology …, 2014 - academic.oup.com
Despite the importance, the diversity of the human infant gut microbiota still remains poorly
characterized at the regional scale. Here, we investigated the faecal microbiota diversity in a …
characterized at the regional scale. Here, we investigated the faecal microbiota diversity in a …
Genetic strategies for sex-biased persistence of gut microbes across human life
C Tarracchini, G Alessandri, F Fontana… - Nature …, 2023 - nature.com
Although compositional variation in the gut microbiome during human development has
been extensively investigated, strain-resolved dynamic changes remain to be fully …
been extensively investigated, strain-resolved dynamic changes remain to be fully …
Evolutionary dynamics of bacteria in the gut microbiome within and across hosts
Gut microbiota are shaped by a combination of ecological and evolutionary forces. While the
ecological dynamics have been extensively studied, much less is known about how species …
ecological dynamics have been extensively studied, much less is known about how species …