[HTML][HTML] Prenatal stress leads to deficits in brain development, mood related behaviors and gut microbiota in offspring

Z Zhang, N Li, R Chen, T Lee, Y Gao, Z Yuan, Y Nie… - Neurobiology of …, 2021 - Elsevier
Early exposure to stressful and adverse life events at fetal and neonatal stages is one of
crucial risk factors for mood disorders such as anxiety and depressive disorder in adulthood …

Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring

TL Gur, AV Palkar, T Rajasekera, J Allen… - Behavioural brain …, 2019 - Elsevier
In utero and early neonatal exposure to maternal stress is linked with psychiatric disorders,
and the underlying mechanisms are currently being elucidated. We used a prenatal stressor …

Prenatal stress effects on offspring brain and behavior: Mediators, alterations and dysregulated epigenetic mechanisms

SU Haq, UA Bhat, A Kumar - Journal of biosciences, 2021 - Springer
Prenatal environment significantly influences mammalian fetal development and adverse in
utero conditions have life-long consequences for the offspring health. Research has …

Prenatal stress affects placental cytokines and neurotrophins, commensal microbes, and anxiety-like behavior in adult female offspring

TL Gur, L Shay, AV Palkar, S Fisher, VA Varaljay… - Brain, behavior, and …, 2017 - Elsevier
Recent studies demonstrate that exposure to stress changes the composition of the
intestinal microbiota, which is associated with development of stress-induced changes to …

Prenatal stress enhances postnatal plasticity: The role of microbiota

S Hartman, K Sayler, J Belsky - Developmental Psychobiology, 2019 - Wiley Online Library
Separate fields of inquiry indicate (a) that prenatal stress is associated with heightened
behavioral and physiological reactivity and (b) that these postnatal phenotypes are …

Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood

AV Golubeva, S Crampton, L Desbonnet… - …, 2015 - Elsevier
Early-life adverse experiences, including prenatal stress (PNS), are associated with a higher
prevalence of neurodevelopmental, cardiovascular and metabolic disorders in affected …

Early life stress and the development of the infant gut microbiota: implications for mental health and neurocognitive development

SC Vogel, NH Brito, BL Callaghan - Current Psychiatry Reports, 2020 - Springer
Abstract Purpose of Review We review the state of the literature examining associations
between early life stress (ELS), gut microbiota, and neurocognitive development and mental …

The effect of prenatal stress on offspring depression susceptibility in relation to the gut microbiome and metabolome

Q Li, H Sun, J Guo, X Zhao, R Bai, M Zhang… - Journal of affective …, 2023 - Elsevier
Prenatal stress (PS) increases offspring susceptibility to depression, but the underlying
mechanism remains unclear. Our previous results showed that PS can affect depression-like …

Current understanding of the roles of gut–brain Axis in the cognitive deficits caused by perinatal stress exposure

MR Rubinstein, AL Burgueño, S Quiroga, MR Wald… - Cells, 2023 - mdpi.com
The term 'perinatal environment'refers to the period surrounding birth, which plays a crucial
role in brain development. It has been suggested that dynamic communication between the …

A review of the impact of maternal prenatal stress on offspring microbiota and metabolites

V Yeramilli, R Cheddadi, J Shah, K Brawner, C Martin - Metabolites, 2023 - mdpi.com
Maternal prenatal stress exposure affects the development of offspring. We searched for
articles in the PubMed database and reviewed the evidence for how prenatal stress alters …