Background The microbial population of the human gut (the gut microbiome) is an integral
cog in the bidirectional communication axis that exists between the gastrointestinal tract and …

Early-life stress has pervasive, typically detrimental, effects on physical and mental health
across the lifespan. In rats, maternal-separation stress results in premature expression of an …

Uncovering mechanisms underlying fetal programming during pregnancy is of critical
importance. Atypical neurodevelopment during the pre-and immediate postnatal period has …

Prenatal stress (PNS) is associated with neuropsychiatric disorders in offspring, including
anxiety, depression, and autism spectrum disorders. There is mounting evidence that these …

Background Psychosocial stress and mood-related disorders, such as depression, are
prevalent and vulnerability to these conditions is heightened during pregnancy …

The gut microbiota is increasingly recognized as a key environmental factor that shapes host
development and physiology, including neural circuits formation and function. Concurrently …

Highlights•Stressful events during the perinatal period are associated with dysbiosis in the
offspring.•Stress in early life can impact the development and functioning of the …

The accumulation of adverse events in utero and during childhood differentially increases
the vulnerability to psychiatric diseases in men and women. Gut microbiota is highly …

Perturbations in the prenatal and early life environment can contribute to the development of
offspring stress dysregulation, a pervasive symptom in neuropsychiatric disease …

Providing the appropriate quantity and quality of food needed for both the mother's well-
being and the healthy development of the offspring is crucial during pregnancy. However …