Research over the last several years has greatly advanced our understanding of the
mechanisms by which the immune system functions. There exist two main branches of …

Immunological memory is an important evolutionary trait that improves host survival upon
reinfection. Memory is a characteristic recognized within both the innate and adaptive arms …

The mammalian immune system comprises an adaptive and an innate component. The
innate immune system employs a limited number of germ-line-encoded pattern-recognition …

Vaccination is the most effective means of preventing infectious diseases. Despite the
success of many vaccines, there is presently little knowledge of the immunological …

The mammalian immune system has evolved under continuous selective pressure from a
wide range of microorganisms that colonize and replicate in animal hosts. A complex set of …

The ability to remember a previous encounter with pathogens was long thought to be a key
feature of the adaptive immune system enabling the host to mount a faster, more specific …

Receptors of the innate immune system detect conserved determinants of microbial and viral
origin. Activation of these receptors initiates signaling events that culminate in an effective …

Researchers gathered at the Wellcome Trust Genome Campus in Hinxton, Cambridge, for
the first Innate Immune Memory Conference dedicated to the adaptive characteristics of …

Research over the past few years has begun to provide significant advances in our
understanding of the interplay between the innate and adaptive immune systems. New …

The innate arm of the immune system has generally been regarded as primitive and non-
specific and, in contrast to adaptive immunity, not to possess memory. Here we review the …