The ability of pathogenesis-related proteins of family 10 to bind a broad spectrum of ligands
is considered to play a key role for their physiological and pathological functions. In …

Many allergens share several biophysical characteristics, including the capability to undergo
oligomerization. The dimerization mechanism in Bet v 1 and its allergenic properties are so …

The term allergy was coined in 1906 by the Austrian scientist and pediatrician Clemens
Freiherr von Pirquet. In 1976, Dietrich Kraft became the head of the Allergy and Immunology …

Each spring millions of patients suffer from allergies when birch pollen is released into the
air. In most cases, the major pollen allergen Bet v 1 is the elicitor of the allergy symptoms …

Background Birch pollen allergy represents the main cause of winter and spring pollinosis in
the temperate climate zone of the northern hemisphere and sensitization towards Bet v 1 …

Bet v 1 is a 17-kDa protein abundantly present in the pollen of the White birch tree and is the
primary cause of birch pollen allergy in humans. Its three-dimensional structure is …

Background The major birch pollen allergen, Bet v 1, is a member of the ubiquitous PR-10
family of plant pathogenesis-related proteins. In recent years, a number of diverse plant …

Birch pollinosis is one of the prevailing allergic diseases. In all, 5–20% of birch pollinotics
mount IgE antibodies against the minor birch pollen allergen Bet v 4, a Ca2+-binding …

The major birch pollen allergen Bet v 1 is the main elicitor of airborne type I allergies and
belongs to the PR-10 family (pathogenesis-related proteins 10). Bet v 1 is the most …

The 159 residue Bet v 1 is the major allergen from birch tree pollen. Its natural function is
unknown although it is capable of binding several types of physiologically relevant ligands …