[HTML][HTML] Ligand binding modulates the structural dynamics and compactness of the major birch pollen allergen
S Grutsch, JE Fuchs, R Freier, S Kofler, M Bibi… - Biophysical …, 2014 - cell.com
Pathogenesis-related plant proteins of class-10 (PR-10) are essential for storage and
transport of small molecules. A prominent member of the PR-10 family, the major birch …
transport of small molecules. A prominent member of the PR-10 family, the major birch …
[HTML][HTML] Isoforms of Bet v 1, the Major Birch Pollen Allergen, Analyzed by Liquid Chromatography, Mass Spectrometry, and cDNA Cloning (∗)
I Swoboda, A Jilek, F Ferreira, E Engel… - Journal of Biological …, 1995 - ASBMB
Bet v 1, the major allergen of birch pollen, displays a considerable degree of heterogeneity.
Several charge variants have been detected by two-dimensional IgE immunoblots and …
Several charge variants have been detected by two-dimensional IgE immunoblots and …
Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis
MD Spangfort, O Mirza, H Ipsen… - The Journal of …, 2003 - journals.aai.org
Specific allergy vaccination is an efficient treatment for allergic disease; however, the
development of safer vaccines would enable a more general use of the treatment …
development of safer vaccines would enable a more general use of the treatment …
Naturally occurring hypoallergenic Bet v 1 isoforms fail to induce IgE responses in individuals with birch pollen allergy
BACKGROUND: Engineered hypoallergens are currently being investigated for specific
immunotherapy of allergic diseases in preclinical and clinical studies. Naturally occurring …
immunotherapy of allergic diseases in preclinical and clinical studies. Naturally occurring …
Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier
Bet v 1l is a naturally occurring hypoallergenic isoform of the major birch pollen allergen Bet
v 1. The Bet v 1 protein belongs to the ubiquitous family of pathogenesis-related plant …
v 1. The Bet v 1 protein belongs to the ubiquitous family of pathogenesis-related plant …
[HTML][HTML] Secondary structure and tertiary fold of the birch pollen allergen Bet v 1 in solution
Bet v 1 is the major birch pollen allergen and therefore the main cause of type I allergies
observed in early spring. It is composed of 159 amino acid residues adding up to a …
observed in early spring. It is composed of 159 amino acid residues adding up to a …
Cross-reactivity of pollen and food allergens: soybean Gly m 4 is a member of the Bet v 1 superfamily and closely resembles yellow lupine proteins
H Berkner, P Neudecker, D Mittag… - Bioscience …, 2009 - portlandpress.com
In many cases, patients allergic to birch pollen also show allergic reactions after ingestion of
certain fruits or vegetables. This observation is explained at the molecular level by cross …
certain fruits or vegetables. This observation is explained at the molecular level by cross …
[HTML][HTML] Isotype-specific binding patterns of serum antibodies to multiple conformational epitopes of Bet v 1
S Schmalz, V Mayr, A Shosherova, B Gepp… - Journal of Allergy and …, 2022 - Elsevier
Background Birch pollen is an important elicitor of respiratory allergy. The major allergen,
Bet v 1, binds IgE exclusively via conformational epitopes. Objective We identified Bet v 1 …
Bet v 1, binds IgE exclusively via conformational epitopes. Objective We identified Bet v 1 …
Molecular characterization, expression inescherichia coli, and epitope analysis of a two EF-hand calcium-binding birch pollen allergen, Bet v 4
A Twardosz, B Hayek, S Seiberler, L Vangelista… - Biochemical and …, 1997 - Elsevier
Birch pollen belongs to the most potent elicitors of Type I allergic reactions in early spring.
Using serum IgE from a birch pollen allergic patient, two cDNA clones (clone 6 and clone …
Using serum IgE from a birch pollen allergic patient, two cDNA clones (clone 6 and clone …
Biological and immunological importance of Bet v 1 isoforms
M Breitenbach, F Ferreira, A Jilek, I Swoboda… - New Horizons in Allergy …, 1996 - Springer
In 2D-PAGE analysis of Bet v 1, the major birch pollen allergen, up to 12 isoforms can be
demonstrated that differ in their isoelectric points from about pH 4.9 to pH 5.9. The molecular …
demonstrated that differ in their isoelectric points from about pH 4.9 to pH 5.9. The molecular …