The three-dimensional structure of the major birch pollen allergen, the 17,500 M r acidic
protein Bet v 1 (from the birch, Betula verrucosa), is presented as determined both in the …

A gene encoding the pollen major allergen Bet v 1 fromBetula verrucosa (White Birch) has
been cloned and expressed inEscherichia colias a fusion with maltose-binding protein and …

The major birch pollen allergen Bet v 1 is present in pollen as a mixture of at least 14
isoforms that share high sequence and structural identities. These isoforms possess either a …

In type I allergy, the cross-linking of membrane IgE on B lymphocytes and of cytophilic IgE
on effector cells by their respective allergens are key events. For cross-linking two IgE …

Patients allergic to birch pollen often also react with fruits and vegetables, such as apple.
The major cause of cross-reactivity between birch and apple is biochemical and …

Bet v 1, the major birch pollen allergen, is a member of a multigene family; a number of
isoforms and homologous proteins from closely related species (alder, hazel and hornbeam) …

Birch pollen allergy is predominantly caused by the major allergen Bet v 1 and can lead to
crossreactions with homologous proteins in food. Two major cross‐reactive food allergens …

To the Editor, More than twenty different isoforms of Bet v 1, the major birch pollen allergen,
have been identified, sharing an amino acid sequence identity of 95% and an almost …

Background Over 100 million people worldwide suffer from birch pollen allergy. Bet v 1 has
been identified as the major birch pollen allergen. However, the molecular mechanisms of …

The major birch pollen allergen Bet v 1 is one of the most extensively characterized
allergens both on the molecular and the immunological level. To define conformational B …