Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1–related food allergens

B Jahn-Schmid, A Radakovics, D Lüttkopf… - Journal of allergy and …, 2005 - Elsevier
BACKGROUND: Individuals with birch pollen allergy frequently experience hypersensitivity
reactions to certain foods, primarily because of IgE antibodies specific for the major birch …

Skin test evaluation of genetically engineered hypoallergenic derivatives of the major birch pollen allergen, Bet v 1: results obtained with a mix of two recombinant Bet …

M van Hage-Hamsten, M Kronqvist… - Journal of allergy and …, 1999 - Elsevier
Background: More than 95% of birch pollen–allergic subjects react with the major birch
pollen allergen, Bet v 1, and almost 60% of them are sensitized exclusively to this allergen …

Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins

M Chruszcz, MA Ciardiello, T Osinski, KA Majorek… - Molecular …, 2013 - Elsevier
The allergen Act d 11, also known as kirola, is a 17 kDa protein expressed in large amounts
in ripe green and yellow-fleshed kiwifruit. Ten percent of all kiwifruit-allergic individuals …

[HTML][HTML] Identification of a natural ligand of the hazel allergen Cor a 1

T Jacob, CS von Loetzen, A Reuter, U Lacher… - Scientific Reports, 2019 - nature.com
Hazelnut is one of the most frequent causes of food allergy. The major hazel allergen in
Northern Europe is Cor a 1, which is homologous to the major birch pollen allergen Bet v 1 …

Multiplicity of cross‐reactive epitopes on Bet v I as detected with monoclonal antibodies and human IgE

JH Akkerdaas, R Van Ree, M Aalbers, SO Stapel… - Allergy, 1995 - Wiley Online Library
Six monoclonal antibodies against Bet v I, the major cross‐reactive allergen of birch pollen
(Betula verrucosa), were obtained. Four did not react with fruits, but two monoclonal …

Allergen mimotopes for 3‐dimensional epitope search and induction of antibodies inhibiting human IgE

E Ganglberger, K Grunberger, RV Guntaka… - The FASEB …, 2000 - Wiley Online Library
There is no definite information available on the structural characteristics of IgE binding
epitopes on allergenic molecules, although it is widely accepted that most of them are …

Release of Bet v 1 from birch pollen from 5 European countries. Results from the HIALINE study

JTM Buters, M Thibaudon, M Smith, R Kennedy… - Atmospheric …, 2012 - Elsevier
Exposure to allergens is pivotal in determining sensitization and allergic symptoms in
individuals. Pollen grain counts in ambient air have traditionally been assessed to estimate …

[HTML][HTML] The major birch pollen allergen Bet v 1 induces different responses in dendritic cells of birch pollen allergic and healthy individuals

U Smole, C Radauer, N Lengger, M Svoboda, N Rigby… - PloS one, 2015 - journals.plos.org
Dendritic cells play a fundamental role in shaping the immune response to allergens. The
events that lead to allergic sensitization or tolerance induction during the interaction of the …

Characterization of Api g 1.0201, a new member of the Api g 1 family of celery allergens

K Hoffmann-Sommergruber, R Ferris, M Pec… - International archives of …, 2000 - karger.com
Background: The association of pollinosis with allergy to plant foods occurs in up to 70% of
tree pollen-allergic patients. In recent years, some of the relevant cross-reacting proteins …

Structural relatedness of plant food allergens with specific reference to cross-reactive allergens: an in silico analysis

JA Jenkins, S Griffiths-Jones, PR Shewry… - Journal of Allergy and …, 2005 - Elsevier
BACKGROUND: The body of sequence and structural information on allergens and the
sequence analysis of whole plant genomes are facilitating the application of bioinformatic …