[HTML][HTML] Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth
S Schinner, F Engelhardt, M Preusse, JG Thöming… - Biofilm, 2020 - Elsevier
Pseudomonas aeruginosa is an environmental bacterium and an opportunistic human
pathogen. It is also a well-established model organism to study bacterial adaptation to …
pathogen. It is also a well-established model organism to study bacterial adaptation to …
[HTML][HTML] Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
JG Thöming, J Tomasch, M Preusse, M Koska… - npj Biofilms and …, 2020 - nature.com
Studying parallel evolution of similar traits in independent within-species lineages provides
an opportunity to address evolutionary predictability of molecular changes underlying …
an opportunity to address evolutionary predictability of molecular changes underlying …
Divergent molecular strategies drive evolutionary adaptation to competitive fitness in biofilm formation
M Tang, R Yang, Z Zhuang, S Han, Y Sun, P Li… - The ISME …, 2024 - academic.oup.com
Biofilm is a group of heterogeneously structured and densely packed bacteria with limited
access to nutrients and oxygen. These intrinsic features can allow a mono-species biofilm to …
access to nutrients and oxygen. These intrinsic features can allow a mono-species biofilm to …
Use of In-Biofilm Expression Technology To Identify Genes Involved in Pseudomonas aeruginosa Biofilm Development
A Finelli, CV Gallant, K Jarvi, LL Burrows - Journal of bacteriology, 2003 - Am Soc Microbiol
Mature Pseudomonas aeruginosa biofilms form complex three-dimensional architecture and
are tolerant of antibiotics and other antimicrobial compounds. In this work, an in vivo …
are tolerant of antibiotics and other antimicrobial compounds. In this work, an in vivo …
Genetic determinants of Pseudomonas aeruginosa biofilm establishment
The establishment of bacterial biofilms on surfaces is a complex process that requires
various factors for each consecutive developmental step. Here we report the screening of …
various factors for each consecutive developmental step. Here we report the screening of …
[HTML][HTML] Identification of Genes Involved in Pseudomonas aeruginosa Biofilm-Specific Resistance to Antibiotics
L Zhang, M Fritsch, L Hammond, R Landreville… - PloS one, 2013 - journals.plos.org
Pseudomonas aeruginosa is a key opportunistic pathogen characterized by its biofilm
formation ability and high-level multiple antibiotic resistance. By screening a library of …
formation ability and high-level multiple antibiotic resistance. By screening a library of …
[HTML][HTML] A previously uncharacterized gene, PA2146, contributes to biofilm formation and drug tolerance across the ɣ-Proteobacteria
MF Kaleta, OE Petrova, C Zampaloni… - npj Biofilms and …, 2022 - nature.com
Transcriptomic studies have revealed a large number of uncharacterized genes that are
differentially expressed in biofilms, which may be important in regulating biofilm phenotypes …
differentially expressed in biofilms, which may be important in regulating biofilm phenotypes …
Massively parallel transposon mutagenesis identifies temporally essential genes for biofilm formation in Escherichia coli
Biofilms complete a life cycle where cells aggregate, grow and produce a structured
community before dispersing to colonize new environments. Progression through this life …
community before dispersing to colonize new environments. Progression through this life …
Identification of potential antimicrobial targets of Pseudomonas aeruginosa biofilms through a novel screening approach
JDP Valentin, S Altenried, AR Varadarajan… - Microbiology …, 2023 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen of considerable medical
importance, owing to its pronounced antibiotic tolerance and association with cystic fibrosis …
importance, owing to its pronounced antibiotic tolerance and association with cystic fibrosis …
[HTML][HTML] Temperature-specific adaptations and genetic requirements in a biofilm formed by Pseudomonas aeruginosa
Pseudomonas aeruginosa is a gram-negative opportunistic pathogen often associated with
nosocomial infections that are made more severe by this bacterium's ability to form robust …
nosocomial infections that are made more severe by this bacterium's ability to form robust …