Amiodarone (AMI), a widely used, effective anti‐arrhythmic drug, has severe side effects,
including acute lung toxicity and pulmonary fibrosis. Our aim is to test the hypothesis that a …

Associated with amiodarone (AM) therapy is pneumonitis, which may progress to life-
threatening pulmonary fibrosis. Although the etiology of amiodarone-induced pulmonary …

Amiodarone (AM) is an efficacious antidysrhythmic agent that is associated with numerous
adverse effects, including potentially life-threatening pulmonary fibrosis. The current …

Toinvestigate the hypotheses that amiodarone-induced pulmonary inflammation may be
related to direct drug toxicity, groups of 10or more Wistar rats were fed amiodarone by …

In previous studies, we showed that Fischer rats fed 175 mg/kg of amiodarone accumulated
large amounts of drug and metabolite in the lung and developed pulmonary toxicity …

Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …

Amiodarone (AM), a drug used in the treatment of cardiac dysrrhythmias, can produce
severe pulmonary adverse effects, including fibrosis. Although the pathogenesis of AM …

Amiodarone (AM) is an effective antidysrhythmic agent, restricted in use by the development
of adverse effects, including potentially fatal AM‐induced pulmonary toxicity (AIPT). Although …

Amiodarone (AM) is an efficacious antidysrhythmic agent. However, its clinical use is limited
by life-threatening pulmonary toxicity. The morphological effects of AM on cultured lung …

Amiodarone (AM), a potent antidysrhythmic agent, can cause potentially life-threatening
pulmonary fibrosis. In the present investigation of mechanisms of initiation of AM lung …