Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients
develop the disease in late life, named late onset AD (LOAD). Currently, the most …

Abstract Alzheimer's disease (AD), an extremely common neurodegenerative disorder of the
older generation, is one of the leading causes of death globally. Besides the conventional …

Alzheimer's disease (AD) is a neurodegenerative disorder with no clear causative event
making the disease difficult to diagnose and treat. The pathological hallmarks of AD include …

Alzheimer's disease (AD) is the most common form of dementia, affecting more than 50
million people worldwide with an estimated increase to 139 million people by 2050. The …

Alzheimer's disease is a progressive neurodegenerative disease, and its incidence is
expected to increase owing to the aging population worldwide. Current therapies merely …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …

In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Neuroinflammation is now recognized as a prominent feature in Alzheimer's pathology and
a potential target for therapy aimed at treatment and prevention of disease. This review …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by destructive
alterations of neurons (neurofibrillary tangles and amyloid plaques), and cognitive …

Although amyloid-β (Aβ) peptide accumulation is considered as a key early event in the
pathogenesis of Alzheimer's disease (AD), the precise pathophysiology of this deadly illness …