Micro-compartment specific T2⁎ relaxation in the brain

P Sati, P van Gelderen, AC Silva, DS Reich, H Merkle… - Neuroimage, 2013 - Elsevier
MRI at high field can be sensitized to the magnetic properties of tissues, which introduces a
signal dependence on the orientation of white matter (WM) fiber bundles relative to the …

Myelin water imaging depends on white matter fiber orientation in the human brain

C Birkl, J Doucette, M Fan… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose The multi‐exponential T2 decay of the MRI signal from cerebral white matter can be
separated into short T2 components related to myelin water and long T2 components related …

[HTML][HTML] B0-field dependence of MRI T1 relaxation in human brain

Y Wang, P van Gelderen, JA de Zwart, JH Duyn - NeuroImage, 2020 - Elsevier
Tissue longitudinal relaxation characterized by recovery time T 1 or rate R 1 is a
fundamental MRI contrast mechanism that is increasingly being used to study the brain's …

Mechanisms of T2* anisotropy and gradient echo myelin water imaging

J Lee, Y Nam, JY Choi, EY Kim, SH Oh… - NMR in …, 2017 - Wiley Online Library
In MRI, structurally aligned molecular or micro‐organization (eg axonal fibers) can be a
source of substantial signal variations that depend on the structural orientation and the …

[HTML][HTML] Measuring compartmental T2-orientational dependence in human brain white matter using a tiltable RF coil and diffusion-T2 correlation MRI

CMW Tax, E Kleban, M Chamberland, M Baraković… - Neuroimage, 2021 - Elsevier
The anisotropy of brain white matter microstructure manifests itself in orientational-
dependence of various MRI contrasts, and can result in significant quantification biases if …

Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields

C Labadie, JH Lee, WD Rooney… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose Magnetic resonance T1‐weighted images are routinely used for human brain
segmentation, brain parcellation, and clinical diagnosis of demyelinating diseases. Myelin is …

Characterizing healthy and diseased white matter using quantitative magnetization transfer and multicomponent T2 relaxometry: A unified view via a four‐pool model

IR Levesque, GB Pike - … in Medicine: An Official Journal of the …, 2009 - Wiley Online Library
Nuclear magnetic resonance relaxation and magnetization transfer in cerebral white matter
can be described using a four‐pool model: two for water protons (in separate myelin and …

In vivo quantification of T2⁎ anisotropy in white matter fibers in marmoset monkeys

P Sati, AC Silva, P van Gelderen, MI Gaitan, JE Wohler… - Neuroimage, 2012 - Elsevier
T2⁎-weighted MRI at high field is a promising approach for studying noninvasively the
tissue structure and composition of the brain. However, the biophysical origin of T2⁎ …

[HTML][HTML] T1 relaxometry of crossing fibres in the human brain

S De Santis, Y Assaf, B Jeurissen, DK Jones… - NeuroImage, 2016 - Elsevier
A comprehensive tract-based characterisation of white matter should include the ability to
quantify myelin and axonal attributes irrespective of the complexity of fibre organisation …

Insight into in vivo magnetization exchange in human white matter regions

S Kalantari, C Laule, TA Bjarnason… - Magnetic resonance …, 2011 - Wiley Online Library
Water exchange can play an important role in interpreting compartment‐specific magnetic
resonance imaging data in brain. For example, an MR method of myelin measurement …