Background Acute kidney injury (AKI) is a common complication of sepsis, contributing to an
increased mortality rate. However, some studies have demonstrated that renal function …

Background Sepsis prognosis correlates with antibiotic adequacy at the early phase. This
adequacy is dependent on antibacterial spectrum, bacterial resistance profile and antibiotic …

Background Acute kidney injury (AKI) is a potential complication of systemic infection.
Optimizing antimicrobial dosing in this dynamic state can be challenging with sub-or supra …

Optimal dosing of antimicrobial therapy is pivotal to increase the likelihood of survival in
critically ill patients with sepsis. Drug exposure that maximizes bacterial killing, minimizes …

Objective The purpose of this study was to analyze the improvement effect of clinical
pharmacist intervention on renal function impairment in patients with antimicrobial-induced …

Background: Acute kidney injury (AKI) remains a common sequela of sepsis necessitating
use of continuous renal replacement therapy (CRRT). In the setting of AKI, renally adjusted …

A common cause of acute kidney injury (AKI) is sepsis, which makes appropriate dosing of
antibiotics in these patients essential. Drug dosing in critically ill patients with AKI, however …

Although early and appropriate antibiotic therapy remains the most important intervention for
successful treatment of septic shock, data guiding optimization of beta-lactam prescription in …

Acute kidney injury (AKI) remains a very common occurrence in critically ill patients and is
associated with decreased survival in severe sepsis [1]. Effective treatment for these patients …

Objective To describe the incidence and outcomes associated with early acute kidney injury
(AKI) in septic shock and explore the association between duration from hypotension onset …