Malaria, a parasite vector-borne disease, is one of the greatest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …

Doxycycline, a synthetically derived tetracycline, is a partially efficacious causal prophylactic
(liver stage of Plasmodium) drug and a slow acting blood schizontocidal agent highly …

Malaria, a parasite vector-borne disease, is one of the most significant health threats in
tropical regions, despite the availability of individual chemoprophylaxis. Malaria …

Anti-malarial drug resistance to chloroquine and sulfadoxine–pyrimethamine has spread
from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to …

The resistance of Plasmodium falciparum to the chloroquine–proguanil association (C/P) as
antimalarial chemoprophylaxis is becoming increasingly common in Africa. Daily oral …

In the past 21 years, a modest increase in the range of antimalarial drugs approved for
clinical use has been complemented by a more impressive expansion in the analysis and …

Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is
an inexpensive broad-spectrum antimicrobial agent largely used in the management of …

A decline in our ability to successfully treat patients with malaria infections of the parasitic
protozoan Plasmodium falciparum with cheap quinoline drugs has led to a huge escalation …

Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action
remains uncertain. To characterize the antimalarial mechanism of tetracyclines, we …

Drug resistant malaria is a major health problem; it poses a threat to the lives of millions of
people and renders it less possible for the worldwide eradication programme to attain its …