Saliva: diagnostics and therapeutic perspectives

N Spielmann, DT Wong - Oral diseases, 2011 - Wiley Online Library
Oral Diseases (2011) 17, 345–354 For the past two decades, salivary diagnostic
approaches have been developed to monitor oral diseases such as periodontal diseases …

Salivary biomarkers for clinical applications

L Zhang, H Xiao, DT Wong - Molecular diagnosis & therapy, 2009 - Springer
For clinical applications such as monitoring health status, disease onset and progression,
and treatment outcome, there are three necessary prerequisites:(i) a simple method for …

A new approach for the diagnosis of systemic and oral diseases based on salivary biomolecules

A Roi, LC Rusu, CI Roi, RE Luca, S Boia… - Disease …, 2019 - Wiley Online Library
Early diagnosis represents the target of contemporary medicine and has an important role in
the prognosis and further treatment. Saliva is a biofluid that generated a high interest among …

[HTML][HTML] Saliva in the diagnosis of diseases

CZ Zhang, XQ Cheng, JY Li, P Zhang, P Yi… - International journal of …, 2016 - nature.com
Saliva is secreted from the salivary glands and has multiple functions, including mouth
cleaning and protection, antibacterial effects and digestion. With the rapid advancement in …

Salivary biomarkers in cancer detection

X Wang, KE Kaczor-Urbanowicz, DTW Wong - Medical Oncology, 2017 - Springer
Cancer is the second most common cause of death in the USA. Its symptoms are often not
specific and absent, until the tumors have already metastasized. Therefore, there is an …

The emerging landscape of salivary diagnostics

Y Zhang, J Sun, CC Lin, E Abemayor… - Periodontology …, 2016 - Wiley Online Library
Saliva contains a variety of biomolecules, including DNA, coding and noncoding RNA,
proteins, metabolites and microbiota. The changes in the salivary levels of these molecular …

[HTML][HTML] Promising applications of human-derived saliva biomarker testing in clinical diagnostics

M Song, H Bai, P Zhang, X Zhou, B Ying - International Journal of Oral …, 2023 - nature.com
Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …

[HTML][HTML] Towards a simple, saliva-based test for the detection of oral cancer. 'Oral fluid (saliva), which is the mirror of the body, is a perfect medium to be explored for …

DT Wong - Expert review of molecular diagnostics, 2006 - Taylor & Francis
Oral cancers annually affect 38,000 people in the USA and hundreds of thousands of others
around the globe. Despite treatment advances, the disease's overall 5-year survival rate has …

Saliva as a diagnostic tool for dental caries, periodontal disease and cancer: is there a need for more biomarkers?

MAR Buzalaf, AC Ortiz, TS Carvalho… - Expert review of …, 2020 - Taylor & Francis
Introduction: A biomarker is a biological indicator of normal or pathogenic processes.
Identification of biomarkers is useful for the prevention, diagnosis and prognosis of diseases …

[HTML][HTML] Saliva and oral diseases

E Martina, A Campanati, F Diotallevi… - Journal of clinical …, 2020 - mdpi.com
Saliva is a fascinating biological fluid which has all the features of a perfect diagnostic tool.
In fact, its collection is rapid, simple, and noninvasive. Thanks to several transport …