Several signaling pathways were involved in M1 (classic) and M2 (alternative) macrophage
polarization. Disruption of M2‐related signaling pathways and improvement of M1‐related …

Background Macrophages are one of the major cell types in the immune system and are
closely related to tumor development, which can be polarized into M1 type with anti-tumor …

Macrophages can polarize into two different states (M1 and M2), which play contrasting
roles during pathogenesis or tissue damage. M1 polarized macrophages produce pro …

Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

Lung cancer (LC) is one of the most common cancer worldwide. Tumor-associated
macrophages (TAMs) are important component of the tumor microenvironment (TME) and …

Macrophages M2 polarization have been taken as an anti-inflammatory progression during
inflammation. Natural plant-derived products, with potential therapeutic and preventive …

Mylabris phalerata (MP) is an insect used in oriental herbal treatments for tumor, tinea
infections, and stroke. Recent studies have shown that tumor‐associated macrophages …

There are many types of nontumor cells, including leukocytes, fibroblasts, and endothelial
cells, in the tumor microenvironment. Among these cells, infiltrating macrophages have …

Macrophages are phagocytic cells with important physiological functions, including the
digestion of cellular debris, foreign substances, and microbes, as well as tissue …

Tumor‐associated macrophages (TAMs) with M2 phenotype play an essential role in tumor
microenvironment (TME) during the progression and development of numerous cancers and …