Naringin ameliorates diabetic nephropathy by inhibiting NADPH oxidase 4

J Zhang, S Yang, H Li, F Chen, J Shi - European Journal of Pharmacology, 2017 - Elsevier
Naringin, a naturally flavanone glycoside, has been previously demonstrated to alleviate
diabetic kidney disease by inhibiting oxidative stress and inflammatory reaction. However …

Naringin alleviates diabetic kidney disease through inhibiting oxidative stress and inflammatory reaction

F Chen, N Zhang, X Ma, T Huang, Y Shao, C Wu… - PLoS …, 2015 - journals.plos.org
Naringin, a flavanone glycoside extracted from Citrus grandis Osbeck, has a wide range of
pharmacological effects. In the present study we aimed at demonstrating the protective effect …

Effect of Baoshenfang Formula on Podocyte Injury via Inhibiting the NOX‐4/ROS/p38 Pathway in Diabetic Nephropathy

F Cui, L Tang, Y Gao, Y Wang, Y Meng… - Journal of Diabetes …, 2019 - Wiley Online Library
Diabetic nephropathy (DN) is a serious kidney‐related complication of type 1 and type 2
diabetes. The Chinese herbal formula Baoshenfang (BSF) shows therapeutic potential in …

Naringenin ameliorates streptozotocin-induced diabetic rat renal impairment by downregulation of TGF-β1 and IL-1 via modulation of oxidative stress correlates with …

S Roy, F Ahmed, S Banerjee, U Saha - Pharmaceutical biology, 2016 - Taylor & Francis
Context: Naringenin, a flavonone and a nutritive antioxidant which is mostly obtained from
grapefruit, orange or tomato skin, has been extensively studied due to its radical scavenging …

Puerarin attenuates diabetic kidney injury through the suppression of NOX4 expression in podocytes

X Li, W Cai, K Lee, B Liu, Y Deng, Y Chen, X Zhang… - Scientific reports, 2017 - nature.com
Radix puerariae, a traditional Chinese herbal medication, has been used to treat patients
with diabetic nephropathy (DN). Several studies demonstrated that puerarin, the active …

Nepeta angustifolia CY Wu improves renal injury in HFD/STZ-induced diabetic nephropathy and inhibits oxidative stress-induced apoptosis of mesangial cells

S Huang, M Tan, F Guo, L Dong, Z Liu, R Yuan… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance As an important medicinal material constituting a variety of
traditional Chinese medicine prescriptions, Nepeta angustifolia CY Wu was used as a folk …

[HTML][HTML] Tanshinone II Aattenuates renal damage in STZ-induced diabetic rats via inhibiting oxidative stress and inflammation

X Chen, R Wu, Y Kong, Y Yang, Y Gao, D Sun, Q Liu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Oxidative stress and inflammation have been demonstrated to be involved in the onset and
promotion of diabetic nephropathy (DN). Tanshinone IIA (Tan) possesses both antioxidant …

[HTML][HTML] Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4

Y Cui, Y Shi, Y Bao, S Wang, Q Hua, Y Liu - Biomedicine & …, 2018 - Elsevier
Diabetes affects a large proportion of population wide across the world and kidney is a main
target organ of diabetic complications. Zingerone is a stable active component derived from …

[HTML][HTML] Nelumbo nucifera leaves extract attenuate the pathological progression of diabetic nephropathy in high-fat diet-fed and streptozotocin-induced diabetic rats

HW Chen, MY Yang, TW Hung, YC Chang… - journal of food and drug …, 2019 - Elsevier
Diabetic nephropathy is not only a common and severe microvascular complication of
diabetes mellitus but also the leading cause of renal failure. Lotus (Nelumbo nucifera) …

Naringin ameliorates experimental diabetic renal fibrosis by inhibiting the ERK1/2 and JNK MAPK signaling pathways

Y Yang, W Gong, C Jin, Z Chen, L Zhang, Y Zou… - Journal of Functional …, 2018 - Elsevier
Aims With the specific pharmacological activities including anti-inflammation, anti-oxidant
and hypoglycemic effects, Naringin may possess the potential to ameliorate diabetic …