The epileptic seizure is a dynamic process involving a rapid transition from normal activity to
a state of hypersynchronous neuronal discharges. Here we investigated the network …

Increase of the extracellular K+ concentration mediates seizure-like synchronized activities
in vitro and was proposed to be one of the main factors underlying epileptogenesis in some …

Dynamic aspects of the propagation of epileptiform activity have so far received little
attention. With the aim of providing new insights about the spatial features of the propagation …

Intracellular and extracellular recordings were made from pyramidal neurons in
hippocampal slices in order to study spontaneous paroxysmal bursting induced by raising …

Epileptic seizures are associated with neuronal hyperactivity. Here, however, we
investigated whether continuous neuronal firing is necessary to maintain electrographic …

Temporal lobe epilepsy is a neurological condition marked by seizures, typically
accompanied by large amplitude synchronous electrophysiological discharges, affecting a …

It is well established that exogenous electric fields can suppress activity obtained in different
models of epileptiform discharge such as penicillin and high potassium. In the low-calcium …

In CA3 neurons of disinhibited hippocampal slice cultures the slow afterhyperpolarisation,
following spontaneous epileptiform burst events, was confirmed to be Ca2+ dependent and …

Rapid Plasticity at Inhibitory and Excitatory Synapses in the Hippocampus Induced by Ictal
Epileptiform Discharges. Lopantsev V, Both M, Draguhn A. Eur J Neurosci 2009; 29 (6) …

Low-voltage fast (LVF)-and hypersynchronous (HYP)-seizure onset patterns can be
recognized in the EEG of epileptic animals and patients with temporal lobe epilepsy. Ripples …