Stress‐induced escalation of alcohol self‐administration, anxiety‐like behavior, and elevated amygdala Avp expression in a susceptible subpopulation of rats

R Barchiesi, K Chanthongdee, E Domi… - Addiction …, 2021 - Wiley Online Library
Comorbidity between alcohol use and anxiety disorders is associated with more severe
symptoms and poorer treatment outcomes than either of the conditions alone. There is a well …

[HTML][HTML] Enhanced negative emotion and alcohol craving, and altered physiological responses following stress and cue exposure in alcohol dependent individuals

R Sinha, HC Fox, KA Hong, K Bergquist… - …, 2009 - nature.com
Chronic alcohol abuse is associated with changes in stress and reward pathways that could
alter vulnerability to emotional stress and alcohol craving. This study examines whether …

Alcohol craving and demand mediate the relation between posttraumatic stress symptoms and alcohol-related consequences.

JC Tripp, LZ Meshesha, JB Teeters… - Experimental and …, 2015 - psycnet.apa.org
Posttraumatic stress (PTS) symptoms are associated with alcohol-related consequences, but
there is a need to understand mediators that may help explain the reasons for this …

The interplay of negative and positive emotion dysregulation on mental health outcomes among trauma-exposed community individuals.

NH Weiss, SR Forkus, AA Contractor… - … , practice, and policy, 2020 - psycnet.apa.org
Objective: Emotion dysregulation is a transdiagnostic construct with relevance to a wide
range of mental health outcomes. A growing literature highlights the contribution of positive …

[HTML][HTML] Early life stress as a predictor of co-occurring alcohol use disorder and post-traumatic stress disorder

RS Lee, LM Oswald, GS Wand - Alcohol research: current reviews, 2018 - ncbi.nlm.nih.gov
During the critical developmental periods of childhood when neural plasticity is high,
exposure to early life stress (ELS) or trauma may lead to enduring changes in physiological …

Sex and gender differences in co-occurring alcohol use disorder and PTSD

TC Saraiya, SE Back, AM Jarnecke, SM Blakey… - Current Addiction …, 2023 - Springer
Abstract Purpose of Review Research demonstrates a strong association between alcohol
use disorder (AUD) and posttraumatic stress disorder (PTSD). However, less is known about …

Higher Emotion Dysregulation and Coping Motives in Alcoholand Marijuana Users

HR Lucke, CR Harbke, EW Mathes… - Substance Use & …, 2021 - Taylor & Francis
Background: Prior research indicates that difficulties in emotion regulation may contribute to
the use of substances (eg alcohol and marijuana) to alleviate negative affect. Therefore, we …

Impulsivity and alcohol use coping motives in a trauma-exposed sample: The mediating role of distress tolerance

EC Marshall-Berenz, AA Vujanovic… - Personality and individual …, 2011 - Elsevier
The present investigation examined the mediating role of distress tolerance in the
association between impulsivity and alcohol use coping motives among trauma-exposed …

The neural, behavioral, and epidemiological underpinnings of comorbid alcohol use disorder and post-traumatic stress disorder

HN Carlson, JL Weiner - International review of neurobiology, 2021 - Elsevier
Alcohol use disorder (AUD) and (PTSD) frequently co-occur and individuals suffering from
this dual diagnosis often exhibit increased symptom severity and poorer treatment outcomes …

Sex and context differences in the effects of trauma on comorbid alcohol use and post‐traumatic stress phenotypes in actively drinking rats

D Kirson, MQ Steinman, SA Wolfe… - Journal of …, 2021 - Wiley Online Library
Alcohol use disorder (AUD) and affective disorders are frequently comorbid and share
underlying mechanisms that could be targets for comprehensive treatment. Post‐traumatic …