Isothermal titration calorimetry (ITC) is becoming widely accepted as a key instrument in any
laboratory in which quantification of biomolecular interactions is a requisite. The method has …

Over the last decade isothermal titration calorimetry (ITC) has developed from a specialist
method which was largely restricted in its use to dedicated experts, to a major, commercially …

Elucidation of the energetic principles of binding affinity and specificity is a central task in
many branches of current sciences: biology, medicine, pharmacology, chemistry, material …

The market for commercially available isothermal titration calorimeters continues to grow as
new applications and methodologies are developed. Concomitantly the number of users …

Isothermal titration calorimetry (ITC) is a fast, accurate and label‐free method for measuring
the thermodynamics and binding affinities of molecular associations in solution. Because the …

Isothermal titration calorimetry (ITC) can provide a full thermodynamic characterization of an
interaction. Its usage does not suffer from constraints of molecular size, shape or chemical …

Isothermal titration calorimetry (ITC) is a fast and robust method to determine the energetics
of association reactions in solution. The changes in enthalpy, entropy and heat capacity that …

Isothermal titration calorimetry (ITC) is widely employed to measure thermodynamic
properties of binding interactions between two macromolecules or a macromolecule and a …

The chapter is an effort to provide in-depth knowledge about the basic principles involved in
isothermal titration calorimetry (ITC) technique along with practical considerations. It is an …

Calorimetry is a classical biophysical method that by definition measures heat. In isothermal
titration calorimetry (ITC), the heat is the result of titrating interacting components together …