Human T-cell lymphotropic virus type 1 and its oncogenesis

L Zhang, J Wei, L Wang, S Huang… - Acta Pharmacologica …, 2017 - nature.com
Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiologic agent of adult T-cell
leukemia/lymphoma (ATL), a rapidly progressing clonal malignancy of CD4+ T lymphocytes …

HTLV-1 alters T cells for viral persistence and transmission

A Tanaka, M Matsuoka - Frontiers in microbiology, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a
causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory …

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

H Tarokhian, H Rahimi, A Mosavat, A Shirdel… - BMC cancer, 2018 - Springer
Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of
HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load …

Human T-Cell Leukemia Virus Type 1 Oncogenesis between Active Expression and Latency: A Possible Source for the Development of Therapeutic Targets

F Marino-Merlo, S Grelli, A Mastino, M Lai… - International Journal of …, 2023 - mdpi.com
The human T-cell leukemia virus type 1 (HTLV-1) is the only known human oncogenic
retrovirus. HTLV-1 can cause a type of cancer called adult T-cell leukemia/lymphoma (ATL) …

Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …

HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma

BJY Tan, K Sugata, O Reda, M Matsuo… - The Journal of …, 2021 - Am Soc Clin Investig
Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …

HTLV-1-mediated epigenetic pathway to adult T-cell leukemia–lymphoma

M Yamagishi, D Fujikawa, T Watanabe… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1), the first reported human oncogenic retrovirus,
is the etiologic agent of highly aggressive, currently incurable diseases such as adult T-cell …

HTLV-1 HBZ viral protein: a key player in HTLV-1 mediated diseases

M Baratella, G Forlani, RS Accolla - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic human retrovirus that has
infected 10–15 million people worldwide. After a long latency, 3–5% of infected individuals …

HTLV-1 bZIP factor: the key viral gene for pathogenesis

M Matsuoka, JM Mesnard - Retrovirology, 2020 - Springer
Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL)
and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in …

Strategies of human T-cell leukemia virus Type 1 for persistent infection: Implications for leukemogenesis of adult T-cell leukemia-lymphoma

J Yasunaga - Frontiers in microbiology, 2020 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) establishes persistent infection in vivo in two
distinct ways: de novo infection and clonal proliferation of infected cells. Two viral genes …