DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan

E Falisse, B Ducos, PA Stockwell, IM Morison… - Environmental …, 2018 - Elsevier
There is increasing evidence that toxicant exposure can alter DNA methylation profile, one
of the main epigenetic mechanisms, particularly during embryogenesis when DNA …

Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB 126)

N Aluru, SI Karchner, KS Krick, W Zhu… - Environmental …, 2018 - academic.oup.com
There is growing evidence that environmental toxicants can affect various physiological
processes by altering DNA methylation patterns. However, very little is known about the …

Acute/chronic triclosan exposure induces downregulation of m6A-RNA methylation modification via mettl3 suppression and elicits developmental and immune toxicity …

Q Qian, Q Pu, X Li, XC Liu, A Ni, X Han, Z Wang… - Chemosphere, 2024 - Elsevier
Triclosan (TCS), a prevalent contaminant in aquatic ecosystems, has been identified as a
potential threat to both aquatic biota and human health. Despite its widespread presence …

Zebrafish as a model to study the role of DNA methylation in environmental toxicology

JH Kamstra, P Aleström, JM Kooter, J Legler - Environmental Science and …, 2015 - Springer
Environmental epigenetics is a rapidly growing field which studies the effects of
environmental factors such as nutrition, stress, and exposure to compounds on epigenetic …

Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations

PA Olsvik, TD Williams, H Tung, L Mirbahai… - … and Physiology Part C …, 2014 - Elsevier
This study aimed to investigate whether dioxin (TCDD) and methylmercury (MeHg) pose a
threat to offspring of fish exposed to elevated concentrations of these chemicals via …

Development of a screening system for the detection of chemically induced DNA methylation alterations in a zebrafish liver cell line

E Farmen, MT Hultman, MA d'Auriac… - Journal of Toxicology …, 2014 - Taylor & Francis
Early molecular events with correlation to disease, such as aberrant DNA methylation,
emphasize the importance of DNA methylation as a potential environmental biomarker …

Environmental chemicals differentially affect epigenetic-related mechanisms in the zebrafish liver (ZF-L) cell line and in zebrafish embryos

M Blanc, J Rüegg, N Scherbak, SH Keiter - Aquatic Toxicology, 2019 - Elsevier
A number of chemicals have been shown to affect epigenetic patterning and functions. Since
epigenetic mechanisms regulate transcriptional networks, epigenetic changes induced by …

[HTML][HTML] Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish

JH Kamstra, S Hurem, LM Martin, LC Lindeman… - Scientific reports, 2018 - nature.com
Ionizing radiation is known to cause DNA damage, yet the mechanisms underlying potential
transgenerational effects of exposure have been scarcely studied. Previously, we observed …

Dissolved humic substances initiate DNA-methylation in cladocerans

S Menzel, R Bouchnak, R Menzel, CEW Steinberg - Aquatic Toxicology, 2011 - Elsevier
DNA-methylation is one pathway of epigenetic programming of gene expression and can be
responsive to environmental challenges such as methylating agents in the food. Here we …

Patterns of DNA methylation in animals: an ecotoxicological perspective

JA Head - Integrative and Comparative Biology, 2014 - academic.oup.com
DNA methylation refers to the addition of a methyl group to nucleotides within DNA. As with
other epigenetic endpoints, patterns of DNA methylation are susceptible to alterations due to …