Rapid ganciclovir susceptibility assay using flow cytometry for human cytomegalovirus clinical isolates

JJ McSharry, NS Lurain, GL Drusano… - Antimicrobial agents …, 1998 - Am Soc Microbiol
Rapid, quantitative, and objective determination of the susceptibilities of human
cytomegalovirus (HCMV) clinical isolates to ganciclovir has been assessed by an assay that …

Flow cytometric determination of ganciclovir susceptibilities of human cytomegalovirus clinical isolates

JM McSharry, NS Lurain, GL Drusano… - Journal of Clinical …, 1998 - Am Soc Microbiol
ABSTRACT A flow cytometric assay has been developed for the measurement of
susceptibilities to ganciclovir of laboratory strains and clinical isolates of human …

Rapid screening for resistance to ganciclovir and foscarnet of primary isolates of human cytomegalovirus from culture-positive blood samples

G Gerna, A Sarasini, E Percivalle… - Journal of clinical …, 1995 - Am Soc Microbiol
A rapid screening assay for the detection of resistance to ganciclovir and foscarnet of
primary isolates of human cytomegalovirus from culture-positive blood samples was …

Rapid determination of human cytomegalovirus susceptibility to ganciclovir directly from clinical specimen primocultures

JM Pepin, F Simon, A Dussault, G Collin… - Journal of clinical …, 1992 - Am Soc Microbiol
We were able to rapidly determine the susceptibility of human cytomegalovirus to ganciclovir
using a late antigen synthesis reduction assay directly on primocultures of clinical …

In vitro susceptibility of cytomegalovirus isolates from immunocompromised patients to acyclovir and ganciclovir

NL Cole, HH Balfour Jr - Diagnostic microbiology and infectious disease, 1987 - Elsevier
Fifty-four isolates of cytomegalovirus (CMV) from 25 immunocompromised patients with
CMV infections were examined in a plaque reduction assay to determine in vitro …

Antiviral susceptibility testing of cytomegalovirus: criteria for detecting resistance to antivirals

WL Drew, R Miner, E Saleh - Clinical and diagnostic virology, 1993 - Elsevier
Testing cytomegaloviruses for antiviral susceptibility is increasing especially since the
reports of 'resistance'to ganciclovir and foscarnet (Erice et al., 1989; Knox et al., 1991). There …

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir

SC Stanat, JE Reardon, A Erice… - Antimicrobial Agents …, 1991 - Am Soc Microbiol
Cytomegalovirus strains with reduced in vitro susceptibilities to ganciclovir have been
recovered from patients who failed long-term ganciclovir therapy. The ganciclovir-resistant …

Antiviral susceptibility testing of cytomegalovirus from primary culture using shell vial assay to detect the late viral antigen

SM Lipson, LF Tseng, MH Kaplan, FX Biondo - Diagnostic microbiology and …, 1993 - Elsevier
Susceptibility testing of 68 cytomegalovirus (CMV) peripheral blood isolates to Ganciclovir
(DHPG) and 11 blood isolates to Foscarnet (PFA), was performed on primary culture isolates …

The use of flow cytometry to detect antiviral resistance in human cytomegalovirus

AM Kesson, F Zeng, AL Cunningham… - Journal of virological …, 1998 - Elsevier
A method for detecting the antiviral susceptibility of human cytomegalovirus (HCMV) isolates
to antiviral agents using flow cytometry was developed. This method has been used to …

Use of time-saving flow cytometry for rapid determination of resistance of human cytomegalovirus to ganciclovir

GC Lee, DG Lee, SM Choi, JH Yoo… - Journal of clinical …, 2005 - Am Soc Microbiol
There are two ways to assess the susceptibility of human cytomegalovirus (HCMV) to
ganciclovir (GCV): one is a genotypic test that detects resistance-related mutations and the …