Two methods of membrane characterization are compared. Both methods are based on the
permeation of dilute solutions containing probe solutes through a membrane. The first …

The potential of mean force (PMF) of a phospholipid in a bilayer is a key thermodynamic
property that describes the energetic cost of localized lipid defects. We have calculated the …

Stationary electrical conductance experiments together with nonstationary relaxation
experiments allow a quantitative determination of rate constants describing carrier-mediated …

The permeability of lecithin bilayer membranes to nonelectrolytes is in reasonable
agreement with Overton's rule. The is, Pd alpha DKhc, where/Pd is the permeability …

Permeability coefficients (P m) across planar egg lecithin/decane bilayers and bulk
hydrocarbon/water partition coefficients (K w→ hc) have been measured for 24 solutes with …

Facilitated diffusion normally involves mobile carriers, reactive groups which react with
specific solutes and diffuse with them across a liquid membrane. Facilitated diffusion can …

Permeation of many small molecules through lipid bilayers can be directly observed in
molecular dynamics simulations on the nano-and microsecond timescale. While unbiased …

A theoretical treatment of the electrical conductance and tracer permeability of lipid bilayer
membranes in the presence of macrocyclic ion carriers is given. The analysis is based on …

A generalized microscopic mechanism for the facilitated transport of a neutral solute through
a fixed site carrier membrane is given. A series mass transfer resistance model is used to …