The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials

F Wang, Y Li, B Wang, J Li, Z Peng - Critical Care, 2023 - Springer
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human
trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 …

Mesenchymal stem cells: current clinical progress in ARDS and COVID-19

K Xiao, F Hou, X Huang, B Li, ZR Qian, L Xie - Stem Cell Research & …, 2020 - Springer
Acute respiratory distress syndrome (ARDS) develops rapidly and has a high mortality rate.
Survivors usually have low quality of life. Current clinical management strategies are …

Intrapulmonary autologous transplant of bone marrow-derived mesenchymal stromal cells improves lipopolysaccharide-induced acute respiratory distress syndrome …

MR Mokhber Dezfouli, M Jabbari Fakhr… - Critical Care, 2018 - Springer
Background Lung diseases such as acute respiratory distress syndrome (ARDS) have a
high incidence worldwide. The current drug therapies for ARDS have supportive effects …

Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome

W Qu, Z Wang, JM Hare, G Bu… - Stem Cells …, 2020 - academic.oup.com
Severe cases of COVID-19 infection, often leading to death, have been associated with
variants of acute respiratory distress syndrome (ARDS). Cell therapy with mesenchymal …

Cell-based Therapies for Acute Respiratory Distress Syndrome: Where Are We Now?

GF Curley, CM O'Kane, DF McAuley… - American Journal of …, 2024 - atsjournals.org
There is considerable interest in the potential for cell-based therapies, particularly
mesenchymal stromal cells (MSCs) and their products, as a therapy for acute respiratory …

Mesenchymal stromal cells for acute respiratory distress syndrome (ARDS), sepsis, and COVID-19 infection: optimizing the therapeutic potential

E Gorman, J Millar, D McAuley… - Expert review of …, 2021 - Taylor & Francis
Introduction: Mesenchymal stromal (stem) cell (MSC) therapies are emerging as a promising
therapeutic intervention in patients with Acute Respiratory Distress Syndrome (ARDS) and …

Mesenchymal stromal cell therapy for COVID-19-induced ARDS patients: a successful phase 1, control-placebo group, clinical trial

N Kaffash Farkhad, A Sedaghat, H Reihani… - Stem Cell Research & …, 2022 - Springer
Background Acute respiratory distress syndrome (ARDS) is the devastating complication of
the new COVID-19 pandemic, directly correlated with releasing large amounts of …

Cell-based therapies for coronavirus disease 2019: proper clinical investigations are essential

M Khoury, PRM Rocco, DG Phinney, M Krampera… - Cytotherapy, 2020 - Elsevier
The serious consequences of the global coronavirus disease 2019 (COVID-19) pandemic
have prompted a rapid global response to develop effective therapies that can lessen …

Systematic review and meta-analysis of mesenchymal stromal/stem cells as strategical means for the treatment of COVID-19

H Taufiq, K Shaik Fakiruddin… - Therapeutic …, 2023 - journals.sagepub.com
Background: In coronavirus disease 2019 (COVID-19) patients, elevated levels of
inflammatory cytokines from over stimulation of immune cells have become a concern due to …

A systematic evaluation of the quality of meta-analyses in the critical care literature

A Delaney, SM Bagshaw, A Ferland, B Manns… - Critical care, 2005 - Springer
Introduction Meta-analyses have been suggested to be the highest form of evidence
available to clinicians to guide clinical practice in critical care. The purpose of this study was …