Progress in applying the high-voltage electron microscope to biomedical research

MV King, DF Parsons, JN Turner, BB Chang… - Cell Biophysics, 1980 - Springer
This review attempts a physical definition of the technical problems and achievements in
applying the high-voltage electron microscope (HVEM) to biological and medical research. It …

Secondary electron induced current in scanning transmission electron microscopy: an alternative way to visualize the morphology of nanoparticles

E Vlasov, A Skorikov, A Sánchez-Iglesias… - ACS Materials …, 2023 - ACS Publications
Electron tomography (ET) is a powerful tool to determine the three-dimensional (3D)
structure of nanomaterials in a transmission electron microscope. However, the acquisition …

Conventional transmission electron microscopy imaging beyond the diffraction and information limits

A Rosenauer, FF Krause, K Müller, M Schowalter… - Physical review …, 2014 - APS
There are mainly two complementary imaging modes in transmission electron microscopy
(TEM): Conventional TEM (CTEM) and scanning TEM (STEM). In the CTEM mode the …

Use of sample bias voltage for low-energy high-resolution imaging in the SEM

JR Michael, DC Joy, BJ Griffin - Microscopy and Microanalysis, 2010 - cambridge.org
Low beam voltage operation of the SEM has been shown to produce secondary electron
images with high resolution.[1] The ability to form small electron probes is limited in practice …

A monochromatic, aberration-corrected, dual-beam low energy electron microscope

M Mankos, K Shadman - Ultramicroscopy, 2013 - Elsevier
The monochromatic, aberration-corrected, dual-beam low energy electron microscope (MAD-
LEEM) is a novel instrument aimed at imaging of nanostructures and surfaces at sub …

A short note on how to convert a conventional analytical TEM into an analytical Low Voltage TEM

M Stöger-Pollach - Ultramicroscopy, 2014 - Elsevier
The present work is a short note on the performance of a conventional transmission electron
microscope (TEM) being operated at very low beam energies (below 20 keV). We discuss …

Detecting single-electron events in TEM using low-cost electronics and a silicon strip sensor

LC Gontard, G Moldovan, R Carmona-Galán, C Lin… - …, 2014 - academic.oup.com
There is great interest in developing novel position-sensitive direct detectors for
transmission electron microscopy (TEM) that do not rely in the conversion of electrons into …

High-resolution fast ion microscopy of single whole biological cells

AA Bettiol, Z Mi, F Watt - Applied Physics Reviews, 2016 - pubs.aip.org
High-resolution microscopy techniques have become an essential tool in both biological
and biomedical sciences, enabling the visualization of biological processes at cellular and …

Observations of unstained biological specimens using a low-energy, high-resolution STEM

A Takaoka, T Hasegawa - Microscopy, 2006 - academic.oup.com
Low-energy, high-resolution scanning transmission electron microscopy (STEM) is
introduced as a convenient method for observing unstained biological specimens. By …

Large-Scale Electron Microscopy to Find Nanoscale Detail in Cancer

JL Riesterer, C Bueno, ES Stempinski, SK Adamou… - 2023 - academic.oup.com
Sadly, cancer will touch every person at some point in time. Unfortunately, this collection of
diseases is still not understood enough to provide adequate treatment to all patients …