Objectives Microbial adhesion and biofilms have important implications for human health
and disease. Candida albicans is an opportunistic pathogen which forms drug-resistant …

Candida albicans is the most common etiologic agent of systemic fungal infections with
unacceptably high mortality rates. The existing arsenal of antifungal drugs is very limited and …

Candida albicans remains the main causative agent of candidiasis, one of the most frequent
nosocomial infections, with unacceptably high mortality rates. Biofilm formation is a major …

Methods: To address the pressing need for new antifungals, we have performed a high-
content screen of 20,000 small molecules in a chemical library (NOVACore) to identify …

Biofilms formed by the human fungal pathogen Candida albicans are naturally resistant to
many of the antifungal agents commonly used in the clinic. We screened a library containing …

Candida species have emerged as important and common opportunistic human pathogens,
particularly in immunocompromised individuals. The current antifungal therapies either have …

The human fungal opportunistic pathogen Candida albicans resides in the human gut,
genitourinary tract and on the skin. The majority of infections caused by C. albicans are …

Candida albicans is capable of forming biofilms on a variety of inert and biological surfaces.
Cells in biofilms display phenotypic properties that are radically different from their free …

Candida species represent the main cause of opportunistic fungal infections worldwide, and
Candida albicans remains the most common etiological agent of candidiasis, now the third …

Candida albicans is a fungal pathogen that can form biofilms on medical devices and host
tissue, resulting in serious, life-threatening infections. These fungal biofilms are inherently …