The emerging role of N6-methyladenosine RNA methylation as regulators in cancer therapy and drug resistance

Z Chen, Y Hu, L Jin, F Yang, H Ding, L Zhang… - Frontiers in …, 2022 - frontiersin.org
N6-methyladenosine (m6A) RNA methylation has been considered the most prevalent,
abundant, and conserved internal transcriptional modification throughout the eukaryotic …

[HTML][HTML] The role of m6A RNA methylation in cancer

T Sun, R Wu, L Ming - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Abstract N6-methyladenosine (m6A), the most abundant internal modification of RNA in
eukaryotic cells, has gained increasing attention in recent years. The m6A modification …

N6‐methyladenosine Steers RNA Metabolism and Regulation in Cancer

S Dong, Y Wu, Y Liu, H Weng… - Cancer …, 2021 - Wiley Online Library
As one of the most studied ribonucleic acid (RNA) modifications in eukaryotes, N6‐
methyladenosine (m6A) has been shown to play a predominant role in controlling gene …

The emerging roles of N6-methyladenosine RNA methylation in human cancers

H Shen, Y Lan, Y Zhao, Y Shi, J Jin, W Xie - Biomarker Research, 2020 - Springer
Abstract N6-methyladenosine (m 6 A) is the most abundant form of mRNA modification in
eukaryotes. It affects various aspects of RNA metabolism, including nuclear export …

N6‐methyladenosine (m6A) RNA modification in human cancer

FC Huo, ZM Zhu, DS Pei - Cell proliferation, 2020 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) RNA modification, first discovered in 1974, is the most
prevalent, abundant and penetrating messenger RNA (mRNA) modification in eukaryotes …

Mechanism of N6-methyladenosine modification and its emerging role in cancer

S Zhang - Pharmacology & Therapeutics, 2018 - Elsevier
Abstract N 6-methyladenosine (m 6 A), the most prevalent internal methylation in messenger
RNA (mRNA) that is deposited by m 6 A methyltransferases, removed by m 6 A …

Regulation of gene expression by N6-methyladenosine in cancer

J Liu, BT Harada, C He - Trends in cell biology, 2019 - cell.com
As the most abundant mRNA modification in eukaryotic cells, N 6-methyladenosine (m 6 A)
has recently emerged as an important regulator of gene expression. m 6 A modification can …

Regulatory roles of N6-methyladenosine (m6A) methylation in RNA processing and non-communicable diseases

FA Khan, B Nsengimana, UA Awan, XY Ji, S Ji… - Cancer Gene …, 2024 - nature.com
Post-transcriptional RNA modification is an emerging epigenetic control mechanism in cells
that is important in many different cellular and organismal processes. N6-methyladenosine …

N6-methyladenosine: a potential breakthrough for human cancer

L Liu, Y Wang, J Wu, J Liu, Z Qin, H Fan - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Among more than 100 types of identified RNA modification, N 6-methyladenosine (m 6 A)
modification is the predominant mRNA modification, which regulates RNA splicing …

Mechanism of RNA modification N6-methyladenosine in human cancer

Z Zhou, J Lv, H Yu, J Han, X Yang, D Feng, Q Wu… - Molecular cancer, 2020 - Springer
Since the breakthrough discoveries of DNA and histone modifications, the field of RNA
modifications has gained increasing interest in the scientific community. The discovery of N6 …